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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSN1S1 All Species: 4.24
Human Site: Y145 Identified Species: 18.67
UniProt: P47710 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P47710 NP_001020275.1 185 21671 Y145 Q L N Q L A A Y P Y A V W Y Y
Chimpanzee Pan troglodytes XP_517254 185 21634 Y145 Q L N Q L A A Y P C A V W Y Y
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_854552 126 14694 A88 L D A Y P Y A A W Y F P A Q I
Cat Felis silvestris
Mouse Mus musculus P19228 313 35584 A261 S V V D Q A L A Q F S V Q P F
Rat Rattus norvegicus P02661 284 31783 A190 Q A S L A Q Q A S L A Q K H H
Wallaby Macropus eugenll P28550 302 35863 H175 E R E S L L A H E R D I L V P
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.3 N.A. 29.7 N.A. 25.2 26.4 21.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.9 N.A. 47 N.A. 38.9 41.9 38.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 N.A. 13.3 N.A. 13.3 13.3 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 N.A. 13.3 N.A. 40 33.3 33.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 17 0 17 50 67 50 0 0 50 0 17 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % C
% Asp: 0 17 0 17 0 0 0 0 0 0 17 0 0 0 0 % D
% Glu: 17 0 17 0 0 0 0 0 17 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 17 17 0 0 0 17 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 17 0 0 0 0 0 17 17 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 17 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % K
% Leu: 17 34 0 17 50 17 17 0 0 17 0 0 17 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 34 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 17 0 0 0 34 0 0 17 0 17 17 % P
% Gln: 50 0 0 34 17 17 17 0 17 0 0 17 17 17 0 % Q
% Arg: 0 17 0 0 0 0 0 0 0 17 0 0 0 0 0 % R
% Ser: 17 0 17 17 0 0 0 0 17 0 17 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 17 17 0 0 0 0 0 0 0 0 50 0 17 0 % V
% Trp: 0 0 0 0 0 0 0 0 17 0 0 0 34 0 0 % W
% Tyr: 0 0 0 17 0 17 0 34 0 34 0 0 0 34 34 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _