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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPR12 All Species: 22.73
Human Site: T187 Identified Species: 50
UniProt: P47775 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P47775 NP_005279.1 334 36730 T187 N C L R D E S T C S V V R P L
Chimpanzee Pan troglodytes XP_518685 492 51280 A345 N C L A E R A A C S V V R P L
Rhesus Macaque Macaca mulatta Q864J4 317 34745 H185 L F I A Y Y D H A A V L L C L
Dog Lupus familis XP_543160 334 36746 T187 N C L R D E S T C S V V R P L
Cat Felis silvestris
Mouse Mus musculus P35412 334 36571 T187 N C L R D E S T C S V V R P L
Rat Rattus norvegicus P30951 334 36686 T187 N C L R D E S T C S V V R P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519402 379 40932 T232 N C L R D E S T C S V I R P L
Chicken Gallus gallus XP_425637 332 36571 T185 N C L R D E S T C S V I R P L
Frog Xenopus laevis Q801M1 470 52760 V263 N C I K L R S V C S D I F P L
Zebra Danio Brachydanio rerio Q9I8K8 370 41758 D198 N C I N N L D D C S A V L P L
Tiger Blowfish Takifugu rubipres Q98895 470 52063 V260 N C K R L H S V C S D I F P L
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 41.8 26 97 N.A. 93.7 92.2 N.A. 71.7 88 23.1 27.8 25.3 N.A. N.A. N.A. N.A.
Protein Similarity: 100 54.2 43.1 98.5 N.A. 96.4 96.1 N.A. 81 94.9 41 47.5 41.7 N.A. N.A. N.A. N.A.
P-Site Identity: 100 66.6 13.3 100 N.A. 100 100 N.A. 93.3 93.3 46.6 46.6 53.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 80 33.3 100 N.A. 100 100 N.A. 100 100 66.6 60 60 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 19 0 0 10 10 10 10 10 0 0 0 0 % A
% Cys: 0 91 0 0 0 0 0 0 91 0 0 0 0 10 0 % C
% Asp: 0 0 0 0 55 0 19 10 0 0 19 0 0 0 0 % D
% Glu: 0 0 0 0 10 55 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 0 19 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 28 0 0 0 0 0 0 0 0 37 0 0 0 % I
% Lys: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 64 0 19 10 0 0 0 0 0 10 19 0 100 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 91 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 91 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 64 0 19 0 0 0 0 0 0 64 0 0 % R
% Ser: 0 0 0 0 0 0 73 0 0 91 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 55 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 19 0 0 73 55 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _