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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GCGR All Species: 10
Human Site: S431 Identified Species: 27.5
UniProt: P47871 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P47871 NP_000151.1 477 54009 S431 L W E E R N T S N H R A S S S
Chimpanzee Pan troglodytes XP_523746 477 53848 S431 L W E E Q N S S N H K A S S L
Rhesus Macaque Macaca mulatta Q76LL8 415 47765 V370 Y C F L N S E V R S A I R K R
Dog Lupus familis XP_540487 565 62597 T424 R G E P S T S T C V Y W A L D
Cat Felis silvestris
Mouse Mus musculus Q61606 485 54854 S432 L Q E E R L A S S H G S H M A
Rat Rattus norvegicus P30082 485 55020 A439 S S H G S H M A P A G T C H G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001094505 496 56673 S427 E E Y K H T Y S H A P S A R N
Frog Xenopus laevis O42602 415 47768 V370 Y C F L N S E V R S A V R K R
Zebra Danio Brachydanio rerio XP_691434 531 60989 L466 S P E E K Q M L V S S S Q N G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.1 32 68.3 N.A. 80.6 79.7 N.A. N.A. 66.7 31.6 48.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.9 48.8 74.5 N.A. 86.1 86.1 N.A. N.A. 78.2 47.5 64 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 73.3 0 6.6 N.A. 40 0 N.A. N.A. 6.6 0 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 6.6 26.6 N.A. 60 13.3 N.A. N.A. 40 6.6 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 12 12 0 23 23 23 23 0 12 % A
% Cys: 0 23 0 0 0 0 0 0 12 0 0 0 12 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % D
% Glu: 12 12 56 45 0 0 23 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 23 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 12 0 12 0 0 0 0 0 0 23 0 0 0 23 % G
% His: 0 0 12 0 12 12 0 0 12 34 0 0 12 12 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % I
% Lys: 0 0 0 12 12 0 0 0 0 0 12 0 0 23 0 % K
% Leu: 34 0 0 23 0 12 0 12 0 0 0 0 0 12 12 % L
% Met: 0 0 0 0 0 0 23 0 0 0 0 0 0 12 0 % M
% Asn: 0 0 0 0 23 23 0 0 23 0 0 0 0 12 12 % N
% Pro: 0 12 0 12 0 0 0 0 12 0 12 0 0 0 0 % P
% Gln: 0 12 0 0 12 12 0 0 0 0 0 0 12 0 0 % Q
% Arg: 12 0 0 0 23 0 0 0 23 0 12 0 23 12 23 % R
% Ser: 23 12 0 0 23 23 23 45 12 34 12 34 23 23 12 % S
% Thr: 0 0 0 0 0 23 12 12 0 0 0 12 0 0 0 % T
% Val: 0 0 0 0 0 0 0 23 12 12 0 12 0 0 0 % V
% Trp: 0 23 0 0 0 0 0 0 0 0 0 12 0 0 0 % W
% Tyr: 23 0 12 0 0 0 12 0 0 0 12 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _