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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GCGR All Species: 3.94
Human Site: S436 Identified Species: 10.83
UniProt: P47871 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P47871 NP_000151.1 477 54009 S436 N T S N H R A S S S P G H G P
Chimpanzee Pan troglodytes XP_523746 477 53848 S436 N S S N H K A S S L P G R G P
Rhesus Macaque Macaca mulatta Q76LL8 415 47765 R375 S E V R S A I R K R W H R W Q
Dog Lupus familis XP_540487 565 62597 A429 T S T C V Y W A L D P D M G S
Cat Felis silvestris
Mouse Mus musculus Q61606 485 54854 H437 L A S S H G S H M A P A G P C
Rat Rattus norvegicus P30082 485 55020 C444 H M A P A G T C H G D P C E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001094505 496 56673 A432 T Y S H A P S A R N G A G G C
Frog Xenopus laevis O42602 415 47768 R375 S E V R S A V R K R W H R W Q
Zebra Danio Brachydanio rerio XP_691434 531 60989 Q471 Q M L V S S S Q N G M G I G Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.1 32 68.3 N.A. 80.6 79.7 N.A. N.A. 66.7 31.6 48.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.9 48.8 74.5 N.A. 86.1 86.1 N.A. N.A. 78.2 47.5 64 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 73.3 0 13.3 N.A. 20 0 N.A. N.A. 13.3 0 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 86.6 6.6 33.3 N.A. 40 13.3 N.A. N.A. 40 6.6 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 12 0 23 23 23 23 0 12 0 23 0 0 0 % A
% Cys: 0 0 0 12 0 0 0 12 0 0 0 0 12 0 23 % C
% Asp: 0 0 0 0 0 0 0 0 0 12 12 12 0 0 0 % D
% Glu: 0 23 0 0 0 0 0 0 0 0 0 0 0 12 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 23 0 0 0 23 12 34 23 56 0 % G
% His: 12 0 0 12 34 0 0 12 12 0 0 23 12 0 0 % H
% Ile: 0 0 0 0 0 0 12 0 0 0 0 0 12 0 0 % I
% Lys: 0 0 0 0 0 12 0 0 23 0 0 0 0 0 12 % K
% Leu: 12 0 12 0 0 0 0 0 12 12 0 0 0 0 0 % L
% Met: 0 23 0 0 0 0 0 0 12 0 12 0 12 0 0 % M
% Asn: 23 0 0 23 0 0 0 0 12 12 0 0 0 0 0 % N
% Pro: 0 0 0 12 0 12 0 0 0 0 45 12 0 12 23 % P
% Gln: 12 0 0 0 0 0 0 12 0 0 0 0 0 0 34 % Q
% Arg: 0 0 0 23 0 12 0 23 12 23 0 0 34 0 0 % R
% Ser: 23 23 45 12 34 12 34 23 23 12 0 0 0 0 12 % S
% Thr: 23 12 12 0 0 0 12 0 0 0 0 0 0 0 0 % T
% Val: 0 0 23 12 12 0 12 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 12 0 0 0 23 0 0 23 0 % W
% Tyr: 0 12 0 0 0 12 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _