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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALDH1A3 All Species: 32.73
Human Site: S334 Identified Species: 72
UniProt: P47895 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P47895 NP_000684.2 512 56108 S334 Y S E F V R R S V E Y A K K R
Chimpanzee Pan troglodytes XP_001142882 512 56120 S334 Y S E F V R R S V E Y A K K R
Rhesus Macaque Macaca mulatta XP_001083856 512 56096 S334 Y S E F V R R S V E Y A R K R
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9JHW9 512 56139 S334 Y G E F V R R S V E F A K K R
Rat Rattus norvegicus Q8K4D8 512 56153 S334 Y G E F V R R S V E F A K K R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513932 490 53825 S312 Y P E F V K R S V E Y A K K R
Chicken Gallus gallus O93344 518 56713 S340 Y E E F V R R S V E R A K R R
Frog Xenopus laevis Q6GNL7 902 99964 V727 H D E F V K R V V E E V K K M
Zebra Danio Brachydanio rerio NP_001038210 513 55862 S334 Y E E F V R L S V E R A K N I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SU63 538 58570 S359 Y D E F V E K S K A R A L K R
Baker's Yeast Sacchar. cerevisiae P32872 511 56448 T338 C I A Q S R I T V H E S I Y D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 98.2 N.A. N.A. 93.9 93.5 N.A. 84.7 69.3 30.2 70.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 99.2 N.A. N.A. 97 97 N.A. 91.2 82.4 40.7 84.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 N.A. N.A. 86.6 86.6 N.A. 86.6 80 53.3 66.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 N.A. N.A. 93.3 93.3 N.A. 93.3 86.6 66.6 66.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 52.7 54.1 N.A.
Protein Similarity: N.A. N.A. N.A. 65.6 67.7 N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 60 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 0 0 10 0 82 0 0 0 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 19 0 0 0 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 19 91 0 0 10 0 0 0 82 19 0 0 0 0 % E
% Phe: 0 0 0 91 0 0 0 0 0 0 19 0 0 0 0 % F
% Gly: 0 19 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 10 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 10 0 0 0 0 0 10 0 10 % I
% Lys: 0 0 0 0 0 19 10 0 10 0 0 0 73 73 0 % K
% Leu: 0 0 0 0 0 0 10 0 0 0 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 73 73 0 0 0 28 0 10 10 73 % R
% Ser: 0 28 0 0 10 0 0 82 0 0 0 10 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 91 0 0 10 91 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 82 0 0 0 0 0 0 0 0 0 37 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _