KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HTR5A
All Species:
23.64
Human Site:
S186
Identified Species:
47.27
UniProt:
P47898
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P47898
NP_076917.1
357
40255
S186
F
G
W
G
E
T
Y
S
E
G
S
E
E
C
Q
Chimpanzee
Pan troglodytes
Q9N2D9
365
41472
I199
I
P
L
A
L
I
L
I
L
Y
Y
K
I
Y
R
Rhesus Macaque
Macaca mulatta
XP_001105989
357
40242
S186
F
G
W
G
E
T
Y
S
E
G
S
E
E
C
Q
Dog
Lupus familis
XP_539929
360
40500
S189
F
G
W
G
E
T
Y
S
E
G
S
E
E
C
Q
Cat
Felis silvestris
Mouse
Mus musculus
P30966
357
40786
S186
F
G
W
G
E
T
Y
S
E
P
S
E
E
C
Q
Rat
Rattus norvegicus
P35364
357
40654
S186
F
G
W
G
E
T
Y
S
E
L
S
E
E
C
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512760
161
18413
Chicken
Gallus gallus
XP_425970
356
40497
S184
F
G
W
G
E
T
Y
S
E
D
S
E
E
C
Q
Frog
Xenopus laevis
Q98998
408
45769
K229
K
T
V
K
K
A
E
K
K
K
V
A
D
T
C
Zebra Danio
Brachydanio rerio
NP_001007122
346
39394
S178
G
E
T
Y
S
E
D
S
L
A
C
Q
V
S
Q
Tiger Blowfish
Takifugu rubipres
O42384
416
47013
S178
I
M
R
S
Q
P
S
S
M
A
E
D
R
A
N
Fruit Fly
Dros. melanogaster
P20905
564
60843
D307
I
L
G
N
E
H
E
D
E
E
G
Q
P
I
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.7
98
90.2
N.A.
87.1
88.2
N.A.
34.4
79.8
33.3
76.4
33.6
27.4
N.A.
N.A.
N.A.
Protein Similarity:
100
58.6
99.1
93.6
N.A.
92.1
92.4
N.A.
40.6
87.9
52.7
85.4
56.4
43
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
93.3
93.3
N.A.
0
93.3
0
13.3
6.6
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
93.3
93.3
N.A.
0
93.3
20
20
20
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
9
0
0
0
17
0
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
50
17
% C
% Asp:
0
0
0
0
0
0
9
9
0
9
0
9
9
0
0
% D
% Glu:
0
9
0
0
59
9
17
0
59
9
9
50
50
0
0
% E
% Phe:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
50
9
50
0
0
0
0
0
25
9
0
0
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
25
0
0
0
0
9
0
9
0
0
0
0
9
9
0
% I
% Lys:
9
0
0
9
9
0
0
9
9
9
0
9
0
0
0
% K
% Leu:
0
9
9
0
9
0
9
0
17
9
0
0
0
0
0
% L
% Met:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
9
0
0
0
9
0
0
0
9
0
0
9
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
0
17
0
0
59
% Q
% Arg:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
9
% R
% Ser:
0
0
0
9
9
0
9
67
0
0
50
0
0
9
0
% S
% Thr:
0
9
9
0
0
50
0
0
0
0
0
0
0
9
0
% T
% Val:
0
0
9
0
0
0
0
0
0
0
9
0
9
0
0
% V
% Trp:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
50
0
0
9
9
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _