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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AVPR1B All Species: 12.42
Human Site: S253 Identified Species: 27.33
UniProt: P47901 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P47901 NP_000698.1 424 46971 S253 T W D R P S P S T L A A T T R
Chimpanzee Pan troglodytes XP_525039 424 47111 S253 T W D R P S P S T S A A T T R
Rhesus Macaque Macaca mulatta P56494 389 42895 W228 G L I S F K I W Q N L R L K T
Dog Lupus familis XP_545695 420 46143 S253 A W D R T L P S G P A A A T R
Cat Felis silvestris
Mouse Mus musculus Q9WU02 421 46521 S250 G W P K S S S S A A A A A T R
Rat Rattus norvegicus P48974 425 47067 A254 W D K S S S S A V A T A A T R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520677 428 46480 V267 L G T R P G L V L G P G A G A
Chicken Gallus gallus NP_001026669 425 46208 C263 A A S P S A P C C S Q K G S Q
Frog Xenopus laevis P70031 453 51139 S285 K A H K N G V S T P T T I P S
Zebra Danio Brachydanio rerio XP_683692 410 46696 S243 M I G K A S V S S V T I I S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q868T3 506 55785 P341 A S S R G I I P R A K V K T V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 46.7 81.8 N.A. 80.9 81.1 N.A. 49.2 61.1 22.7 50.2 N.A. 21.7 N.A. N.A. N.A.
Protein Similarity: 100 99 58.2 86.3 N.A. 86 87 N.A. 61.4 73.6 40.6 64.8 N.A. 34.7 N.A. N.A. N.A.
P-Site Identity: 100 93.3 0 60 N.A. 46.6 26.6 N.A. 13.3 6.6 13.3 20 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 93.3 0 60 N.A. 53.3 33.3 N.A. 13.3 26.6 20 46.6 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 28 19 0 0 10 10 0 10 10 28 37 46 37 0 10 % A
% Cys: 0 0 0 0 0 0 0 10 10 0 0 0 0 0 0 % C
% Asp: 0 10 28 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 19 10 10 0 10 19 0 0 10 10 0 10 10 10 0 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 10 0 0 10 19 0 0 0 0 10 19 0 0 % I
% Lys: 10 0 10 28 0 10 0 0 0 0 10 10 10 10 0 % K
% Leu: 10 10 0 0 0 10 10 0 10 10 10 0 10 0 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 10 0 0 0 0 0 % N
% Pro: 0 0 10 10 28 0 37 10 0 19 10 0 0 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 10 % Q
% Arg: 0 0 0 46 0 0 0 0 10 0 0 10 0 0 55 % R
% Ser: 0 10 19 19 28 46 19 55 10 19 0 0 0 19 10 % S
% Thr: 19 0 10 0 10 0 0 0 28 0 28 10 19 55 10 % T
% Val: 0 0 0 0 0 0 19 10 10 10 0 10 0 0 10 % V
% Trp: 10 37 0 0 0 0 0 10 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _