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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NPTX2 All Species: 30.91
Human Site: S25 Identified Species: 75.56
UniProt: P47972 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P47972 NP_002514.1 431 47042 S25 Q D S P A P G S R F V C T A L
Chimpanzee Pan troglodytes XP_001136152 431 47063 S25 Q D S P A P G S R F V C T A L
Rhesus Macaque Macaca mulatta XP_001111081 613 66317 S209 Q D S P A P G S R F V C T A L
Dog Lupus familis XP_546984 433 47288 S27 Q D G P A P G S R F V C T A L
Cat Felis silvestris
Mouse Mus musculus O70340 429 47118 S26 Q D S P I P G S R F V C T A L
Rat Rattus norvegicus P97738 432 47411 S26 Q D N P I P G S R F V C T A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512220 445 48650 S33 P G R P A S G S R F V C T S L
Chicken Gallus gallus XP_414750 489 53230 S29 E R E S P P G S R F V C T S L
Frog Xenopus laevis NP_001091445 435 48766 T27 S A Q N F A Q T R F I C T S V
Zebra Danio Brachydanio rerio NP_001103238 432 47970 N28 G A N G A K G N R F V C T A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 69.3 95.6 N.A. 96.2 95.1 N.A. 83.8 75.6 52.6 65 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 69.3 96 N.A. 96.9 96.3 N.A. 89.8 81.8 70.8 79.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 93.3 86.6 N.A. 66.6 60 26.6 53.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 73.3 73.3 53.3 73.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 20 0 0 60 10 0 0 0 0 0 0 0 70 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % C
% Asp: 0 60 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 100 0 0 0 0 0 % F
% Gly: 10 10 10 10 0 0 90 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 20 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 20 10 0 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 10 0 0 70 10 70 0 0 0 0 0 0 0 0 0 % P
% Gln: 60 0 10 0 0 0 10 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 10 0 0 0 0 0 100 0 0 0 0 0 0 % R
% Ser: 10 0 40 10 0 10 0 80 0 0 0 0 0 30 0 % S
% Thr: 0 0 0 0 0 0 0 10 0 0 0 0 100 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 90 0 0 0 20 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _