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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFP36L2
All Species:
10.3
Human Site:
S125
Identified Species:
20.61
UniProt:
P47974
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P47974
NP_008818.3
494
51063
S125
K
F
R
D
R
S
F
S
E
N
G
D
R
S
Q
Chimpanzee
Pan troglodytes
XP_515435
491
50660
S125
K
F
R
D
R
S
F
S
E
N
G
D
R
S
Q
Rhesus Macaque
Macaca mulatta
XP_001106984
391
39455
G37
M
L
D
K
K
A
V
G
T
P
V
A
A
A
P
Dog
Lupus familis
XP_851565
491
50664
S124
K
F
R
D
R
S
F
S
E
N
G
E
R
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
P23949
367
37574
A14
V
G
T
P
V
A
A
A
P
S
S
S
F
T
P
Rat
Rattus norvegicus
P17431
338
36380
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521042
345
36095
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080610
363
40060
Y10
A
T
L
L
S
A
F
Y
D
I
D
L
L
Y
K
Zebra Danio
Brachydanio rerio
NP_996938
310
34516
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P47980
436
47147
Q83
Q
P
A
Q
L
I
Q
Q
Q
Q
Q
Q
H
Q
Q
Honey Bee
Apis mellifera
XP_001121248
401
42823
G48
G
S
S
G
N
N
G
G
H
A
P
L
R
R
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782811
386
42511
L32
L
I
H
A
K
T
Q
L
R
G
D
T
R
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
78.3
94.1
N.A.
68.2
41.9
N.A.
47.3
N.A.
55.8
41.9
N.A.
24.7
26.3
N.A.
34.6
Protein Similarity:
100
99.3
78.5
95.1
N.A.
69.4
50
N.A.
53.6
N.A.
62.3
50.6
N.A.
37.2
38.8
N.A.
44.9
P-Site Identity:
100
100
0
93.3
N.A.
0
0
N.A.
0
N.A.
6.6
0
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
20
100
N.A.
26.6
0
N.A.
0
N.A.
26.6
0
N.A.
20
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
9
0
25
9
9
0
9
0
9
9
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
25
0
0
0
0
9
0
17
17
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
25
0
0
9
0
0
0
% E
% Phe:
0
25
0
0
0
0
34
0
0
0
0
0
9
0
0
% F
% Gly:
9
9
0
9
0
0
9
17
0
9
25
0
0
0
0
% G
% His:
0
0
9
0
0
0
0
0
9
0
0
0
9
0
0
% H
% Ile:
0
9
0
0
0
9
0
0
0
9
0
0
0
0
0
% I
% Lys:
25
0
0
9
17
0
0
0
0
0
0
0
0
0
9
% K
% Leu:
9
9
9
9
9
0
0
9
0
0
0
17
9
0
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
9
0
0
0
25
0
0
0
0
0
% N
% Pro:
0
9
0
9
0
0
0
0
9
9
9
0
0
0
17
% P
% Gln:
9
0
0
9
0
0
17
9
9
9
9
9
0
9
34
% Q
% Arg:
0
0
25
0
25
0
0
0
9
0
0
0
42
9
0
% R
% Ser:
0
9
9
0
9
25
0
25
0
9
9
9
0
25
0
% S
% Thr:
0
9
9
0
0
9
0
0
9
0
0
9
0
9
0
% T
% Val:
9
0
0
0
9
0
9
0
0
0
9
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
0
0
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _