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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UQCRFS1
All Species:
51.21
Human Site:
S246
Identified Species:
75.11
UniProt:
P47985
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P47985
NP_005994.2
274
29668
S246
H
G
S
H
Y
D
A
S
G
R
I
R
L
G
P
Chimpanzee
Pan troglodytes
Q69BK5
274
29619
S246
H
G
S
H
Y
D
A
S
G
R
I
R
L
G
P
Rhesus Macaque
Macaca mulatta
XP_001101202
274
29734
S246
H
G
S
H
Y
D
A
S
G
R
I
R
L
G
P
Dog
Lupus familis
XP_533711
274
29434
S246
H
G
S
H
Y
D
A
S
G
R
I
R
K
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR68
274
29349
S246
H
G
S
H
Y
D
A
S
G
R
I
R
K
G
P
Rat
Rattus norvegicus
P20788
274
29427
S246
H
G
S
H
Y
D
A
S
G
R
I
R
K
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506483
366
39594
S338
H
G
S
H
Y
D
A
S
G
R
I
R
K
G
P
Chicken
Gallus gallus
Q5ZLR5
272
29368
S244
H
G
S
H
Y
D
A
S
G
R
I
R
K
G
P
Frog
Xenopus laevis
NP_001090500
273
29267
S245
H
G
S
H
Y
D
A
S
G
R
I
R
K
G
P
Zebra Danio
Brachydanio rerio
NP_001096664
273
29695
S245
H
G
S
H
Y
D
A
S
G
R
I
R
K
G
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722715
230
24854
G203
G
S
H
Y
D
A
S
G
R
I
R
K
G
P
A
Honey Bee
Apis mellifera
XP_394657
274
29793
S246
H
G
S
H
Y
D
A
S
G
R
I
R
K
G
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780127
274
29985
S246
H
G
S
H
Y
D
A
S
G
R
I
R
K
G
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P49727
273
29817
S245
H
G
S
H
Y
D
I
S
G
R
I
R
K
G
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P08067
215
23346
G189
G
S
H
Y
D
I
S
G
R
I
R
K
G
P
A
Red Bread Mold
Neurospora crassa
P07056
231
24752
R205
S
H
Y
D
I
S
G
R
I
R
K
G
P
A
P
Conservation
Percent
Protein Identity:
100
99.2
94.5
87.5
N.A.
88.6
89.7
N.A.
59.2
74.4
75.1
69.3
N.A.
55.1
54.7
N.A.
56.5
Protein Similarity:
100
100
97.8
93.4
N.A.
94.5
95.6
N.A.
64.7
83.9
84.6
80.6
N.A.
67.8
72.2
N.A.
70.8
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
93.3
93.3
N.A.
0
93.3
N.A.
93.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
93.3
93.3
N.A.
20
93.3
N.A.
93.3
Percent
Protein Identity:
N.A.
43.8
N.A.
N.A.
44.5
44.1
Protein Similarity:
N.A.
59.8
N.A.
N.A.
60.9
60.2
P-Site Identity:
N.A.
86.6
N.A.
N.A.
0
13.3
P-Site Similarity:
N.A.
86.6
N.A.
N.A.
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
75
0
0
0
0
0
0
7
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
13
82
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
82
0
0
0
0
7
13
82
0
0
7
13
82
0
% G
% His:
82
7
13
82
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
7
7
0
7
13
82
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
7
13
63
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
7
13
88
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
7
13
88
13
82
0
0
0
% R
% Ser:
7
13
82
0
0
7
13
82
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
13
82
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _