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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UQCRFS1 All Species: 25.76
Human Site: S99 Identified Species: 37.78
UniProt: P47985 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P47985 NP_005994.2 274 29668 S99 R R L E V L D S T K S S R E S
Chimpanzee Pan troglodytes Q69BK5 274 29619 S99 R R L E V L D S T K S S R E S
Rhesus Macaque Macaca mulatta XP_001101202 274 29734 S99 R R L E V L D S T K S S R E S
Dog Lupus familis XP_533711 274 29434 G99 R R A E V L D G T K S S K E S
Cat Felis silvestris
Mouse Mus musculus Q9CR68 274 29349 S99 R R A E V L D S T K S S K E S
Rat Rattus norvegicus P20788 274 29427 S99 R R A E V L D S T K S S K E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506483 366 39594 S191 R R A E V S D S T K S S K D S
Chicken Gallus gallus Q5ZLR5 272 29368 T99 E D V M D A T T S S Q T S S E
Frog Xenopus laevis NP_001090500 273 29267 T99 R P E V L D S T K S S Q T S S
Zebra Danio Brachydanio rerio NP_001096664 273 29695 N99 R P E V L N P N K Q S Q E S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_722715 230 24854 G75 A F S Y L M V G A G A V G G A
Honey Bee Apis mellifera XP_394657 274 29793 P99 R H E A V Q D P R S K S K E N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780127 274 29985 P99 R R D T T S D P K K P A S T S
Poplar Tree Populus trichocarpa
Maize Zea mays P49727 273 29817 G105 N H E R Y P P G D P S K R A F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P08067 215 23346 G61 S Y A Y F M V G A M G L L S S
Red Bread Mold Neurospora crassa P07056 231 24752 T77 F S Y F M V G T M G A I T A A
Conservation
Percent
Protein Identity: 100 99.2 94.5 87.5 N.A. 88.6 89.7 N.A. 59.2 74.4 75.1 69.3 N.A. 55.1 54.7 N.A. 56.5
Protein Similarity: 100 100 97.8 93.4 N.A. 94.5 95.6 N.A. 64.7 83.9 84.6 80.6 N.A. 67.8 72.2 N.A. 70.8
P-Site Identity: 100 100 100 80 N.A. 86.6 86.6 N.A. 73.3 0 20 13.3 N.A. 0 33.3 N.A. 33.3
P-Site Similarity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. 86.6 26.6 33.3 33.3 N.A. 26.6 46.6 N.A. 40
Percent
Protein Identity: N.A. 43.8 N.A. N.A. 44.5 44.1
Protein Similarity: N.A. 59.8 N.A. N.A. 60.9 60.2
P-Site Identity: N.A. 13.3 N.A. N.A. 6.6 0
P-Site Similarity: N.A. 13.3 N.A. N.A. 13.3 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 32 7 0 7 0 0 13 0 13 7 0 13 13 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 7 0 7 7 57 0 7 0 0 0 0 7 0 % D
% Glu: 7 0 25 44 0 0 0 0 0 0 0 0 7 44 7 % E
% Phe: 7 7 0 7 7 0 0 0 0 0 0 0 0 0 7 % F
% Gly: 0 0 0 0 0 0 7 25 0 13 7 0 7 7 7 % G
% His: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 19 50 7 7 32 0 0 % K
% Leu: 0 0 19 0 19 38 0 0 0 0 0 7 7 0 0 % L
% Met: 0 0 0 7 7 13 0 0 7 7 0 0 0 0 0 % M
% Asn: 7 0 0 0 0 7 0 7 0 0 0 0 0 0 7 % N
% Pro: 0 13 0 0 0 7 13 13 0 7 7 0 0 0 0 % P
% Gln: 0 0 0 0 0 7 0 0 0 7 7 13 0 0 0 % Q
% Arg: 69 50 0 7 0 0 0 0 7 0 0 0 25 0 0 % R
% Ser: 7 7 7 0 0 13 7 38 7 19 63 50 13 25 63 % S
% Thr: 0 0 0 7 7 0 7 19 44 0 0 7 13 7 0 % T
% Val: 0 0 7 13 50 7 13 0 0 0 0 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 7 13 7 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _