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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UQCRFS1 All Species: 28.48
Human Site: T122 Identified Species: 41.78
UniProt: P47985 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P47985 NP_005994.2 274 29668 T122 Y L V T G V T T V G V A Y A A
Chimpanzee Pan troglodytes Q69BK5 274 29619 T122 Y L V T G V T T V G V A Y A A
Rhesus Macaque Macaca mulatta XP_001101202 274 29734 T122 Y L V T A V T T V G V A Y A A
Dog Lupus familis XP_533711 274 29434 S122 Y L I T A T T S I G V A Y A A
Cat Felis silvestris
Mouse Mus musculus Q9CR68 274 29349 T122 Y L V T A T T T V G V A Y A A
Rat Rattus norvegicus P20788 274 29427 T122 Y L V T A T T T V G V A Y A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506483 366 39594 T214 Y L I T A T T T V G V A Y A A
Chicken Gallus gallus Q5ZLR5 272 29368 A122 V T A T A C V A T A Y A A K N
Frog Xenopus laevis NP_001090500 273 29267 V122 L V T G A T A V A S A Y A A K
Zebra Danio Brachydanio rerio NP_001096664 273 29695 V122 L M T G S T L V V G V Y T A K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_722715 230 24854 A98 T F I G S M S A S A E V L A M
Honey Bee Apis mellifera XP_394657 274 29793 G122 Y V M T A A S G I T G A Y I A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780127 274 29985 T122 Y L L V G G G T I A A T Y G A
Poplar Tree Populus trichocarpa
Maize Zea mays P49727 273 29817 L128 R F I Y A S L L R L L V L K F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P08067 215 23346 A84 T F I S S M T A T A D V L A M
Red Bread Mold Neurospora crassa P07056 231 24752 S100 F L K N M S A S A D V L A M A
Conservation
Percent
Protein Identity: 100 99.2 94.5 87.5 N.A. 88.6 89.7 N.A. 59.2 74.4 75.1 69.3 N.A. 55.1 54.7 N.A. 56.5
Protein Similarity: 100 100 97.8 93.4 N.A. 94.5 95.6 N.A. 64.7 83.9 84.6 80.6 N.A. 67.8 72.2 N.A. 70.8
P-Site Identity: 100 100 93.3 66.6 N.A. 86.6 86.6 N.A. 80 13.3 6.6 26.6 N.A. 6.6 33.3 N.A. 40
P-Site Similarity: 100 100 93.3 86.6 N.A. 86.6 86.6 N.A. 86.6 13.3 13.3 33.3 N.A. 26.6 60 N.A. 53.3
Percent
Protein Identity: N.A. 43.8 N.A. N.A. 44.5 44.1
Protein Similarity: N.A. 59.8 N.A. N.A. 60.9 60.2
P-Site Identity: N.A. 0 N.A. N.A. 13.3 20
P-Site Similarity: N.A. 13.3 N.A. N.A. 33.3 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 57 7 13 19 13 25 13 57 19 69 63 % A
% Cys: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 7 7 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % E
% Phe: 7 19 0 0 0 0 0 0 0 0 0 0 0 0 7 % F
% Gly: 0 0 0 19 19 7 7 7 0 50 7 0 0 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 32 0 0 0 0 0 19 0 0 0 0 7 0 % I
% Lys: 0 0 7 0 0 0 0 0 0 0 0 0 0 13 13 % K
% Leu: 13 57 7 0 0 0 13 7 0 7 7 7 19 0 0 % L
% Met: 0 7 7 0 7 13 0 0 0 0 0 0 0 7 13 % M
% Asn: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 7 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 7 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % R
% Ser: 0 0 0 7 19 13 13 13 7 7 0 0 0 0 0 % S
% Thr: 13 7 13 57 0 38 50 44 13 7 0 7 7 0 0 % T
% Val: 7 13 32 7 0 19 7 13 44 0 57 19 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 57 0 0 7 0 0 0 0 0 0 7 13 57 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _