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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XDH All Species: 17.88
Human Site: S108 Identified Species: 39.33
UniProt: P47989 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P47989 NP_000370.2 1333 146424 S108 V Q E R I A K S H G S Q C G F
Chimpanzee Pan troglodytes XP_525729 1333 146376 S108 V Q E R I A K S H G S Q C G F
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_540143 1333 147201 S108 V Q E R I A K S H G S Q C G F
Cat Felis silvestris
Mouse Mus musculus Q00519 1335 146500 H111 Q E R I A K S H G S Q C G F C
Rat Rattus norvegicus P22985 1331 146224 H108 Q E R I A R S H G S Q C G F C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509432 1297 142673 S108 V Q E R I S K S H G S Q C G F
Chicken Gallus gallus P47990 1358 149595 S112 A Q E R I A K S H G S Q C G F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_688983 1351 148155 A121 V Q E R I A K A H G S Q C G F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10351 1335 146909 A108 V Q E R L A K A H G S Q C G F
Honey Bee Apis mellifera XP_001119950 1356 152206 A131 V Q E R I A K A H G S Q C G F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q7G192 1321 144562 F107 I H K R L S G F H A S Q C G F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 90.4 N.A. 89.1 90.3 N.A. 70.4 72.3 N.A. 67.8 N.A. 52.6 52.4 N.A. N.A.
Protein Similarity: 100 99.6 N.A. 95.4 N.A. 95.1 95.8 N.A. 82.3 84 N.A. 81.4 N.A. 69.5 70.5 N.A. N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 0 0 N.A. 93.3 93.3 N.A. 93.3 N.A. 86.6 93.3 N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 6.6 6.6 N.A. 100 93.3 N.A. 100 N.A. 100 100 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 34.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 52.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 19 64 0 28 0 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 19 82 0 19 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 19 73 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 0 19 82 % F
% Gly: 0 0 0 0 0 0 10 0 19 73 0 0 19 82 0 % G
% His: 0 10 0 0 0 0 0 19 82 0 0 0 0 0 0 % H
% Ile: 10 0 0 19 64 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 0 0 10 73 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 19 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 19 73 0 0 0 0 0 0 0 0 19 82 0 0 0 % Q
% Arg: 0 0 19 82 0 10 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 19 19 46 0 19 82 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 64 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _