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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XDH
All Species:
29.09
Human Site:
T612
Identified Species:
64
UniProt:
P47989
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P47989
NP_000370.2
1333
146424
T612
S
L
R
L
V
T
S
T
R
A
H
A
K
I
K
Chimpanzee
Pan troglodytes
XP_525729
1333
146376
T612
S
L
R
L
V
T
S
T
R
A
H
A
K
I
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540143
1333
147201
T613
S
L
R
L
V
T
S
T
R
A
H
A
K
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q00519
1335
146500
T614
S
L
R
L
V
T
S
T
R
A
H
A
K
I
T
Rat
Rattus norvegicus
P22985
1331
146224
T611
S
L
R
L
V
T
S
T
R
A
H
A
K
I
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509432
1297
142673
Y600
Y
C
D
D
I
P
P
Y
S
N
E
L
Y
L
R
Chicken
Gallus gallus
P47990
1358
149595
T640
Y
L
T
L
V
T
S
T
Q
A
H
A
K
I
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_688983
1351
148155
T631
H
L
A
L
V
T
S
T
K
A
H
A
L
I
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10351
1335
146909
P615
A
F
V
L
S
T
K
P
R
A
K
I
T
K
L
Honey Bee
Apis mellifera
XP_001119950
1356
152206
T637
Y
L
A
V
V
L
S
T
R
A
H
A
K
I
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q7G192
1321
144562
K592
Y
G
A
F
I
Y
S
K
K
P
F
A
R
I
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
90.4
N.A.
89.1
90.3
N.A.
70.4
72.3
N.A.
67.8
N.A.
52.6
52.4
N.A.
N.A.
Protein Similarity:
100
99.6
N.A.
95.4
N.A.
95.1
95.8
N.A.
82.3
84
N.A.
81.4
N.A.
69.5
70.5
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
0
73.3
N.A.
73.3
N.A.
26.6
66.6
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
20
80
N.A.
80
N.A.
33.3
73.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
28
0
0
0
0
0
0
82
0
82
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
10
0
10
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
73
0
0
0
0
% H
% Ile:
0
0
0
0
19
0
0
0
0
0
0
10
0
82
0
% I
% Lys:
0
0
0
0
0
0
10
10
19
0
10
0
64
10
46
% K
% Leu:
0
73
0
73
0
10
0
0
0
0
0
10
10
10
28
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
10
10
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
46
0
0
0
0
0
64
0
0
0
10
0
10
% R
% Ser:
46
0
0
0
10
0
82
0
10
0
0
0
0
0
0
% S
% Thr:
0
0
10
0
0
73
0
73
0
0
0
0
10
0
19
% T
% Val:
0
0
10
10
73
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
37
0
0
0
0
10
0
10
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _