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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP5O All Species: 44.24
Human Site: S180 Identified Species: 74.87
UniProt: P48047 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48047 NP_001688.1 213 23277 S180 L E A K T D P S I L G G M I V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001090216 213 23233 S180 L E A K T D P S I M G G M I V
Dog Lupus familis XP_535587 213 23461 S180 L E V K V D P S I M G G M I V
Cat Felis silvestris
Mouse Mus musculus Q9DB20 213 23345 S180 L E I K T D P S I M G G M I V
Rat Rattus norvegicus Q06647 213 23379 S180 L E V K T D P S I M G G M I V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513754 265 29369 S232 L E V K T D P S I M G G M I V
Chicken Gallus gallus XP_001232545 210 22784 S177 L E T K T D P S V L G G M I V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001003843 209 22464 S177 L E T K S D A S I L G G M I V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24439 209 22404 S176 I T S R V D P S I I G G L I V
Honey Bee Apis mellifera XP_392760 207 22616 S174 L T A K V D P S I M G G M I I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001178536 209 22803 T176 L N L T V D P T L I G G M I V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q96251 238 26303 S200 V E Q K I D P S I Y G G L I V
Baker's Yeast Sacchar. cerevisiae P09457 212 22796 E179 L E N V V K P E I K G G L I V
Red Bread Mold Neurospora crassa Q9P602 220 23028 D187 V T N K V N A D I I G G L V V
Conservation
Percent
Protein Identity: 100 N.A. 97.1 87.7 N.A. 82.1 81.6 N.A. 61.8 63.3 N.A. 61.5 N.A. 42.7 47.4 N.A. 40.8
Protein Similarity: 100 N.A. 98.5 96.7 N.A. 93.4 92 N.A. 74.7 79.8 N.A. 80.2 N.A. 66.6 64.3 N.A. 65.2
P-Site Identity: 100 N.A. 93.3 80 N.A. 86.6 86.6 N.A. 86.6 86.6 N.A. 80 N.A. 53.3 73.3 N.A. 53.3
P-Site Similarity: 100 N.A. 100 86.6 N.A. 93.3 93.3 N.A. 93.3 93.3 N.A. 86.6 N.A. 86.6 86.6 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. 31 34.2 36.8
Protein Similarity: N.A. N.A. N.A. 52.5 55.8 58.1
P-Site Identity: N.A. N.A. N.A. 66.6 53.3 33.3
P-Site Similarity: N.A. N.A. N.A. 80 60 66.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 22 0 0 0 15 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 86 0 8 0 0 0 0 0 0 0 % D
% Glu: 0 72 0 0 0 0 0 8 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 100 100 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 8 0 8 0 0 0 86 22 0 0 0 93 8 % I
% Lys: 0 0 0 79 0 8 0 0 0 8 0 0 0 0 0 % K
% Leu: 79 0 8 0 0 0 0 0 8 22 0 0 29 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 43 0 0 72 0 0 % M
% Asn: 0 8 15 0 0 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 86 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 8 0 8 0 0 79 0 0 0 0 0 0 0 % S
% Thr: 0 22 15 8 43 0 0 8 0 0 0 0 0 0 0 % T
% Val: 15 0 22 8 43 0 0 0 8 0 0 0 0 8 93 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _