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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNJ1
All Species:
25.76
Human Site:
T191
Identified Species:
62.96
UniProt:
P48048
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48048
NP_000211.1
391
44795
T191
R
P
K
K
R
A
K
T
I
T
F
S
K
N
A
Chimpanzee
Pan troglodytes
XP_522246
391
44791
T191
R
P
K
K
R
A
K
T
I
T
F
S
K
N
A
Rhesus Macaque
Macaca mulatta
XP_001113379
391
44839
T191
R
P
K
K
R
A
K
T
I
T
F
S
K
N
A
Dog
Lupus familis
XP_546403
479
54277
T279
R
P
K
K
R
A
K
T
I
T
F
S
K
N
A
Cat
Felis silvestris
Mouse
Mus musculus
O88335
372
42757
R184
K
N
A
V
I
S
K
R
G
G
K
L
C
L
L
Rat
Rattus norvegicus
P35560
391
44945
T191
R
P
K
K
R
A
K
T
I
T
F
S
K
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505779
453
51353
T253
R
S
K
K
C
A
K
T
I
T
F
S
K
N
A
Chicken
Gallus gallus
P52186
427
48500
T192
K
P
K
K
R
N
E
T
L
V
F
S
H
N
A
Frog
Xenopus laevis
NP_001087438
372
42205
R184
K
N
A
V
I
S
K
R
G
G
K
L
C
L
L
Zebra Danio
Brachydanio rerio
NP_001092204
375
42248
Q187
W
K
G
N
L
C
L
Q
I
R
V
A
N
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
97.4
76.4
N.A.
88.2
91
N.A.
76.3
39.8
79.8
57.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
98.4
78.7
N.A.
91.3
94.6
N.A.
81.2
62.5
87.2
70
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
6.6
100
N.A.
86.6
60
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
20
100
N.A.
86.6
80
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
0
0
60
0
0
0
0
0
10
0
0
70
% A
% Cys:
0
0
0
0
10
10
0
0
0
0
0
0
20
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
70
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
20
20
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
20
0
0
0
70
0
0
0
0
0
0
% I
% Lys:
30
10
70
70
0
0
80
0
0
0
20
0
60
0
0
% K
% Leu:
0
0
0
0
10
0
10
0
10
0
0
20
0
30
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
20
0
10
0
10
0
0
0
0
0
0
10
70
0
% N
% Pro:
0
60
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
60
0
0
0
60
0
0
20
0
10
0
0
0
0
10
% R
% Ser:
0
10
0
0
0
20
0
0
0
0
0
70
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
70
0
60
0
0
0
0
0
% T
% Val:
0
0
0
20
0
0
0
0
0
10
10
0
0
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _