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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNJ6
All Species:
26.36
Human Site:
Y351
Identified Species:
58
UniProt:
P48051
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48051
NP_002231.1
423
48451
Y351
D
G
F
Y
E
V
D
Y
N
S
F
H
E
T
Y
Chimpanzee
Pan troglodytes
XP_508857
330
37659
V259
L
N
Q
T
D
I
N
V
G
F
D
T
G
D
D
Rhesus Macaque
Macaca mulatta
XP_001113289
429
48853
Y358
K
G
F
Y
E
V
D
Y
N
T
F
H
D
T
Y
Dog
Lupus familis
XP_544881
428
49021
Y356
D
G
F
Y
E
V
D
Y
N
S
F
H
E
T
Y
Cat
Felis silvestris
Mouse
Mus musculus
P48542
425
48633
Y353
D
G
F
Y
E
V
D
Y
N
S
F
H
E
T
Y
Rat
Rattus norvegicus
P48550
425
48621
Y353
D
G
F
Y
E
V
D
Y
N
S
F
H
E
T
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509759
885
96895
Y813
D
G
F
Y
E
V
D
Y
N
S
F
H
E
T
Y
Chicken
Gallus gallus
Q90854
492
55398
Y334
E
G
F
F
K
V
D
Y
S
Q
F
H
A
T
F
Frog
Xenopus laevis
NP_001156864
429
49473
V358
W
G
H
R
F
I
P
V
L
T
L
E
K
G
F
Zebra Danio
Brachydanio rerio
XP_697984
402
46197
G330
P
V
L
T
L
E
D
G
F
Y
E
V
D
Y
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52192
505
57401
I373
R
S
N
G
S
Y
Q
I
D
Y
D
L
F
H
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60
69.4
97.1
N.A.
97.8
98.3
N.A.
45.9
50.2
67.8
80.8
N.A.
N.A.
N.A.
36.4
N.A.
Protein Similarity:
100
68.3
81.1
97.9
N.A.
99
99
N.A.
47.1
64.4
78.7
87.7
N.A.
N.A.
N.A.
55.8
N.A.
P-Site Identity:
100
0
80
100
N.A.
100
93.3
N.A.
100
53.3
6.6
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
20
93.3
100
N.A.
100
100
N.A.
100
86.6
33.3
13.3
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
46
0
0
0
10
0
73
0
10
0
19
0
19
10
10
% D
% Glu:
10
0
0
0
55
10
0
0
0
0
10
10
46
0
0
% E
% Phe:
0
0
64
10
10
0
0
0
10
10
64
0
10
0
19
% F
% Gly:
0
73
0
10
0
0
0
10
10
0
0
0
10
10
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
64
0
10
10
% H
% Ile:
0
0
0
0
0
19
0
10
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
10
0
10
0
10
0
0
0
10
0
10
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
10
0
0
0
10
0
55
0
0
0
0
0
10
% N
% Pro:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
10
0
0
10
0
0
0
0
0
% Q
% Arg:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
0
10
0
0
0
10
46
0
0
0
0
10
% S
% Thr:
0
0
0
19
0
0
0
0
0
19
0
10
0
64
0
% T
% Val:
0
10
0
0
0
64
0
19
0
0
0
10
0
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
55
0
10
0
64
0
19
0
0
0
10
46
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _