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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CPA2 All Species: 38.18
Human Site: S272 Identified Species: 76.36
UniProt: P48052 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48052 NP_001860.2 419 47030 S272 G A S S N P C S D S Y H G P S
Chimpanzee Pan troglodytes XP_001156440 417 46840 S270 G A S S N P C S D S Y H G P S
Rhesus Macaque Macaca mulatta XP_001095065 406 45349 S259 G A S S N P C S D S Y H G P S
Dog Lupus familis XP_532425 417 46920 S270 G A S N N P C S D S Y H G P H
Cat Felis silvestris
Mouse Mus musculus Q504N0 417 47039 S270 G A S S N P C S D S Y H G P S
Rat Rattus norvegicus P19222 417 46894 S270 G A S S S P C S D S Y H G P K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510965 421 47664 S274 G A S K N P C S D S Y H G P S
Chicken Gallus gallus XP_414978 792 88711 S272 G A S S N P C S D S Y R G P R
Frog Xenopus laevis NP_001088499 420 47261 T273 G S S S N P C T E T Y R G R A
Zebra Danio Brachydanio rerio NP_001002217 417 46955 S270 G A S K N P C S D S Y H G P Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VL86 430 47642 D277 A S S S A C S D T Y A G P S A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38836 430 49811 E283 Y S G E T P F E A W E A S A W
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 90.9 89.9 N.A. 85.9 86.6 N.A. 75 37.3 59 62 N.A. 33 N.A. N.A. N.A.
Protein Similarity: 100 99.2 93.7 93.7 N.A. 91.6 91.8 N.A. 85.2 44.1 75.2 75.1 N.A. 53.4 N.A. N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. 100 86.6 N.A. 93.3 86.6 53.3 86.6 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 93.3 N.A. 93.3 86.6 86.6 86.6 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 47.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 75 0 0 9 0 0 0 9 0 9 9 0 9 17 % A
% Cys: 0 0 0 0 0 9 84 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 9 75 0 0 0 0 0 0 % D
% Glu: 0 0 0 9 0 0 0 9 9 0 9 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % F
% Gly: 84 0 9 0 0 0 0 0 0 0 0 9 84 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 67 0 0 9 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 9 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 75 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 92 0 0 0 0 0 0 9 75 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 17 0 9 9 % R
% Ser: 0 25 92 67 9 0 9 75 0 75 0 0 9 9 42 % S
% Thr: 0 0 0 0 9 0 0 9 9 9 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 9 % W
% Tyr: 9 0 0 0 0 0 0 0 0 9 84 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _