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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CPA2 All Species: 39.09
Human Site: Y316 Identified Species: 78.18
UniProt: P48052 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48052 NP_001860.2 419 47030 Y316 S Q L L M F P Y G Y K C T K L
Chimpanzee Pan troglodytes XP_001156440 417 46840 Y314 S Q L L M F P Y G Y K C T K L
Rhesus Macaque Macaca mulatta XP_001095065 406 45349 Y303 S Q L L M F P Y G Y K C T K P
Dog Lupus familis XP_532425 417 46920 Y314 S Q L L M F P Y G Y T C T K S
Cat Felis silvestris
Mouse Mus musculus Q504N0 417 47039 Y314 S Q L L M F P Y G Y K C A K P
Rat Rattus norvegicus P19222 417 46894 Y314 S Q L L M F P Y G Y K C T K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510965 421 47664 Y318 S Q L L M F P Y G Y K C T N L
Chicken Gallus gallus XP_414978 792 88711 Y316 S Q L L M Y P Y G Y K C T P P
Frog Xenopus laevis NP_001088499 420 47261 Y317 S Q M L L F P Y G Y T T A R T
Zebra Danio Brachydanio rerio NP_001002217 417 46955 Y314 S Q L L M Y P Y G Y T C T N I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VL86 430 47642 Y321 S Q Y L L Y P Y G H T S D L P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38836 430 49811 L327 Y A Y S C D A L P R D L E N L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 90.9 89.9 N.A. 85.9 86.6 N.A. 75 37.3 59 62 N.A. 33 N.A. N.A. N.A.
Protein Similarity: 100 99.2 93.7 93.7 N.A. 91.6 91.8 N.A. 85.2 44.1 75.2 75.1 N.A. 53.4 N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 86.6 N.A. 86.6 93.3 N.A. 93.3 80 53.3 73.3 N.A. 40 N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 86.6 N.A. 86.6 93.3 N.A. 93.3 86.6 73.3 86.6 N.A. 60 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 47.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 9 0 0 0 0 0 17 0 0 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 0 75 0 0 0 % C
% Asp: 0 0 0 0 0 9 0 0 0 0 9 0 9 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % E
% Phe: 0 0 0 0 0 67 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 92 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 59 0 0 50 0 % K
% Leu: 0 0 75 92 17 0 0 9 0 0 0 9 0 9 34 % L
% Met: 0 0 9 0 75 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 25 0 % N
% Pro: 0 0 0 0 0 0 92 0 9 0 0 0 0 9 42 % P
% Gln: 0 92 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 9 0 0 0 9 0 % R
% Ser: 92 0 0 9 0 0 0 0 0 0 0 9 0 0 9 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 34 9 67 0 9 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 17 0 0 25 0 92 0 84 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _