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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CXCL12
All Species:
20.91
Human Site:
S25
Identified Species:
57.5
UniProt:
P48061
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48061
NP_000600.1
93
10666
S25
L
S
D
G
K
P
V
S
L
S
Y
R
C
P
C
Chimpanzee
Pan troglodytes
Q5I1Z0
92
10079
S24
L
C
N
Q
F
S
A
S
L
A
A
D
T
P
T
Rhesus Macaque
Macaca mulatta
Q8HYQ1
91
10000
S28
A
S
A
S
P
H
A
S
D
T
T
P
C
C
F
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P40224
93
10542
S25
I
S
D
G
K
P
V
S
L
S
Y
R
C
P
C
Rat
Rattus norvegicus
P50231
92
10151
S29
V
P
A
S
P
Y
G
S
D
T
T
P
C
C
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512801
92
10467
S25
L
S
E
G
K
P
I
S
L
S
Y
R
C
P
C
Chicken
Gallus gallus
Q90826
90
9951
D27
S
A
A
P
V
G
S
D
P
P
T
S
C
C
F
Frog
Xenopus laevis
Q8UUJ9
94
10682
S25
L
T
E
G
K
P
V
S
L
V
Y
R
C
P
C
Zebra Danio
Brachydanio rerio
NP_840092
99
11319
S27
I
S
N
A
K
P
I
S
L
V
E
R
C
W
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
23.6
29
N.A.
N.A.
92.4
31.1
N.A.
80.6
23.6
63.8
42.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
36.5
47.3
N.A.
N.A.
95.6
47.3
N.A.
90.3
38.7
85.1
70.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
26.6
20
N.A.
N.A.
93.3
13.3
N.A.
86.6
6.6
80
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
26.6
N.A.
N.A.
100
26.6
N.A.
100
13.3
93.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
34
12
0
0
23
0
0
12
12
0
0
0
0
% A
% Cys:
0
12
0
0
0
0
0
0
0
0
0
0
89
34
56
% C
% Asp:
0
0
23
0
0
0
0
12
23
0
0
12
0
0
0
% D
% Glu:
0
0
23
0
0
0
0
0
0
0
12
0
0
0
0
% E
% Phe:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
34
% F
% Gly:
0
0
0
45
0
12
12
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% H
% Ile:
23
0
0
0
0
0
23
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
56
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
45
0
0
0
0
0
0
0
67
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
23
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
12
0
12
23
56
0
0
12
12
0
23
0
56
0
% P
% Gln:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
56
0
0
0
% R
% Ser:
12
56
0
23
0
12
12
89
0
34
0
12
0
0
0
% S
% Thr:
0
12
0
0
0
0
0
0
0
23
34
0
12
0
12
% T
% Val:
12
0
0
0
12
0
34
0
0
23
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% W
% Tyr:
0
0
0
0
0
12
0
0
0
0
45
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _