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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC6A12
All Species:
6.06
Human Site:
S577
Identified Species:
14.81
UniProt:
P48065
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48065
NP_001116319.1
614
69368
S577
R
Q
L
I
T
P
D
S
S
L
P
Q
P
K
Q
Chimpanzee
Pan troglodytes
XP_001152123
629
70224
T589
Q
K
L
T
T
P
S
T
D
L
K
M
R
G
K
Rhesus Macaque
Macaca mulatta
Q9MYX0
630
70239
H572
L
F
Q
Y
N
Y
P
H
W
S
I
I
L
G
Y
Dog
Lupus familis
XP_533741
630
70351
A590
R
K
L
T
I
P
S
A
D
L
K
M
R
G
K
Cat
Felis silvestris
Mouse
Mus musculus
P31651
614
69595
P577
R
R
L
I
T
P
D
P
S
L
P
Q
P
G
R
Rat
Rattus norvegicus
P48056
614
69730
P577
Q
R
L
I
T
P
D
P
S
L
P
Q
P
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416378
1056
118813
T574
I
P
L
F
L
L
E
T
A
L
G
Q
Y
T
S
Frog
Xenopus laevis
A7Y2W8
633
71004
W577
A
V
K
P
S
K
D
W
G
P
A
L
Q
E
H
Zebra Danio
Brachydanio rerio
XP_001922571
585
66696
S546
R
M
G
T
T
K
G
S
L
M
E
R
V
Q
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VR07
943
103618
P876
R
I
R
N
T
L
R
P
N
I
Y
E
C
K
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.7
42
63.6
N.A.
87.4
86.6
N.A.
N.A.
40.9
42.5
64.1
N.A.
28.3
N.A.
N.A.
N.A.
Protein Similarity:
100
76.4
63.1
76.5
N.A.
93.1
92.6
N.A.
N.A.
48.2
63
77.5
N.A.
42.3
N.A.
N.A.
N.A.
P-Site Identity:
100
26.6
0
26.6
N.A.
73.3
66.6
N.A.
N.A.
20
6.6
20
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
53.3
0
46.6
N.A.
86.6
86.6
N.A.
N.A.
40
20
40
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
10
10
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
0
0
40
0
20
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
10
10
0
10
0
% E
% Phe:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
10
0
0
0
10
0
10
0
10
0
0
50
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% H
% Ile:
10
10
0
30
10
0
0
0
0
10
10
10
0
0
10
% I
% Lys:
0
20
10
0
0
20
0
0
0
0
20
0
0
20
20
% K
% Leu:
10
0
60
0
10
20
0
0
10
60
0
10
10
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
10
0
20
0
0
0
% M
% Asn:
0
0
0
10
10
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
10
0
10
0
50
10
30
0
10
30
0
30
0
0
% P
% Gln:
20
10
10
0
0
0
0
0
0
0
0
40
10
10
10
% Q
% Arg:
50
20
10
0
0
0
10
0
0
0
0
10
20
0
20
% R
% Ser:
0
0
0
0
10
0
20
20
30
10
0
0
0
0
10
% S
% Thr:
0
0
0
30
60
0
0
20
0
0
0
0
0
10
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
10
0
0
0
0
10
0
10
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _