KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PREP
All Species:
46.06
Human Site:
S250
Identified Species:
77.95
UniProt:
P48147
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48147
NP_002717.3
710
80700
S250
D
G
R
Y
V
L
L
S
I
R
E
G
C
D
P
Chimpanzee
Pan troglodytes
XP_518657
710
80695
S250
D
G
R
Y
V
L
L
S
I
R
E
G
C
D
P
Rhesus Macaque
Macaca mulatta
XP_001087580
710
80763
S250
D
G
R
Y
V
L
L
S
I
R
E
G
C
D
P
Dog
Lupus familis
XP_854289
651
73567
E237
E
Y
D
Y
V
T
N
E
G
T
V
F
T
F
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9QUR6
710
80733
S250
D
G
R
Y
V
L
L
S
I
W
E
G
C
D
P
Rat
Rattus norvegicus
O70196
710
80723
S250
D
G
R
Y
V
L
L
S
I
W
E
G
C
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505853
734
82688
S274
D
G
R
Y
V
L
L
S
I
R
Q
G
C
D
P
Chicken
Gallus gallus
NP_001006410
710
80772
S250
D
G
R
Y
V
L
L
S
I
R
E
G
C
D
P
Frog
Xenopus laevis
NP_001084314
712
80625
S253
D
G
Q
Y
V
L
L
S
I
R
E
G
C
D
P
Zebra Danio
Brachydanio rerio
NP_001018589
709
80318
S249
D
G
R
Y
V
L
L
S
I
R
E
G
C
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395364
765
87125
T310
C
G
K
W
L
I
V
T
P
V
K
D
C
R
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002306966
733
82736
Y262
D
G
K
Y
L
L
L
Y
I
E
E
S
C
D
P
Maize
Zea mays
NP_001130392
731
81856
G260
D
G
K
Y
I
I
L
G
I
Y
E
G
C
D
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_177741
795
89386
S324
D
G
K
Y
L
I
M
S
I
G
E
S
C
D
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.8
87.6
N.A.
95.7
95.2
N.A.
86.2
90.2
81.5
76
N.A.
N.A.
55.2
N.A.
N.A.
Protein Similarity:
100
100
99.5
89.5
N.A.
98.5
98.3
N.A.
92.3
95.9
91
89.3
N.A.
N.A.
70.5
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
93.3
93.3
N.A.
93.3
100
93.3
100
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
93.3
93.3
N.A.
100
100
100
100
N.A.
N.A.
60
N.A.
N.A.
Percent
Protein Identity:
55.6
54.5
N.A.
52.4
N.A.
N.A.
Protein Similarity:
73.2
72.5
N.A.
68.1
N.A.
N.A.
P-Site Identity:
66.6
66.6
N.A.
60
N.A.
N.A.
P-Site Similarity:
80
86.6
N.A.
86.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
93
0
0
% C
% Asp:
86
0
8
0
0
0
0
0
0
0
0
8
0
86
8
% D
% Glu:
8
0
0
0
0
0
0
8
0
8
79
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% F
% Gly:
0
93
0
0
0
0
0
8
8
8
0
72
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
22
0
0
86
0
0
0
0
0
0
% I
% Lys:
0
0
29
0
0
0
0
0
0
0
8
0
0
0
8
% K
% Leu:
0
0
0
0
22
72
79
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
86
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
58
0
0
0
0
0
0
50
0
0
0
8
0
% R
% Ser:
0
0
0
0
0
0
0
72
0
0
0
15
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
8
0
8
0
0
8
0
0
% T
% Val:
0
0
0
0
72
0
8
0
0
8
8
0
0
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
15
0
0
0
0
0
% W
% Tyr:
0
8
0
93
0
0
0
8
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _