KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ME1
All Species:
13.03
Human Site:
S47
Identified Species:
22.05
UniProt:
P48163
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48163
NP_002386.1
572
64150
S47
I
H
G
L
L
P
P
S
F
N
S
Q
E
I
Q
Chimpanzee
Pan troglodytes
XP_518610
768
84121
S225
I
H
G
L
L
P
P
S
F
N
S
Q
E
I
Q
Rhesus Macaque
Macaca mulatta
XP_001084781
572
63996
S47
I
H
G
L
L
P
P
S
F
I
S
Q
E
I
Q
Dog
Lupus familis
XP_532217
634
71129
C109
I
H
G
L
L
P
P
C
F
I
S
Q
D
I
Q
Cat
Felis silvestris
Mouse
Mus musculus
P06801
572
63980
C47
I
H
G
L
L
P
P
C
I
I
S
Q
E
L
Q
Rat
Rattus norvegicus
P13697
572
63984
C47
I
H
G
L
L
P
P
C
I
V
N
Q
E
I
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512855
562
62388
L49
D
I
Q
V
L
R
V
L
K
N
F
E
R
L
T
Chicken
Gallus gallus
NP_989634
557
61982
I47
Q
D
V
Q
V
L
T
I
L
K
N
F
E
R
L
Frog
Xenopus laevis
NP_001088519
613
67458
C91
I
H
G
L
L
P
P
C
F
L
S
Q
D
V
Q
Zebra Danio
Brachydanio rerio
NP_001082825
603
66722
C81
I
H
G
L
L
P
P
C
F
L
S
Q
D
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395280
537
59737
S44
D
R
Y
D
N
D
L
S
K
Y
I
Y
L
I
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780686
581
64710
V61
I
H
G
L
L
P
P
V
I
S
S
M
E
L
Q
Poplar Tree
Populus trichocarpa
P34105
591
65205
T84
L
R
G
L
L
P
P
T
T
I
S
Q
Q
L
Q
Maize
Zea mays
P16243
636
69805
A129
L
R
G
L
L
P
P
A
V
L
S
Q
E
L
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.3
95
82.6
N.A.
89.3
90.3
N.A.
79.3
75.8
68.8
68.4
N.A.
N.A.
57.6
N.A.
59.7
Protein Similarity:
100
74.4
97
86.5
N.A.
94.9
95.9
N.A.
89.3
88.4
80.5
82
N.A.
N.A.
73.4
N.A.
75.7
P-Site Identity:
100
100
93.3
80
N.A.
73.3
73.3
N.A.
13.3
6.6
73.3
73.3
N.A.
N.A.
13.3
N.A.
66.6
P-Site Similarity:
100
100
93.3
86.6
N.A.
80
80
N.A.
33.3
20
86.6
86.6
N.A.
N.A.
13.3
N.A.
80
Percent
Protein Identity:
48
44
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
65.4
61
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
53.3
60
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
80
80
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
36
0
0
0
0
0
0
0
% C
% Asp:
15
8
0
8
0
8
0
0
0
0
0
0
22
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
8
58
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
43
0
8
8
0
0
0
% F
% Gly:
0
0
79
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
65
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
65
8
0
0
0
0
0
8
22
29
8
0
0
43
0
% I
% Lys:
0
0
0
0
0
0
0
0
15
8
0
0
0
0
0
% K
% Leu:
15
0
0
79
86
8
8
8
8
22
0
0
8
36
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
22
15
0
0
0
0
% N
% Pro:
0
0
0
0
0
79
79
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
8
8
0
0
0
0
0
0
0
72
8
0
79
% Q
% Arg:
0
22
0
0
0
8
0
0
0
0
0
0
8
8
0
% R
% Ser:
0
0
0
0
0
0
0
29
0
8
72
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
8
8
8
0
0
0
0
0
8
% T
% Val:
0
0
8
8
8
0
8
8
8
8
0
0
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
8
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _