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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ME1
All Species:
15.45
Human Site:
T526
Identified Species:
26.15
UniProt:
P48163
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48163
NP_002386.1
572
64150
T526
K
D
A
Y
Q
E
K
T
A
T
V
Y
P
E
P
Chimpanzee
Pan troglodytes
XP_518610
768
84121
T722
K
D
A
Y
Q
E
K
T
A
T
V
Y
P
E
P
Rhesus Macaque
Macaca mulatta
XP_001084781
572
63996
T526
K
D
A
Y
Q
E
K
T
A
T
V
Y
P
E
P
Dog
Lupus familis
XP_532217
634
71129
T588
K
D
A
Y
Q
E
K
T
A
T
V
Y
P
E
P
Cat
Felis silvestris
Mouse
Mus musculus
P06801
572
63980
M526
Q
D
A
Y
K
E
K
M
A
T
V
Y
P
E
P
Rat
Rattus norvegicus
P13697
572
63984
M526
Q
D
A
Y
K
E
K
M
A
T
V
Y
P
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512855
562
62388
L516
E
E
A
Y
Q
K
N
L
A
S
I
H
P
E
P
Chicken
Gallus gallus
NP_989634
557
61982
R512
R
I
A
E
E
A
Y
R
N
N
T
A
T
T
Y
Frog
Xenopus laevis
NP_001088519
613
67458
N568
I
V
D
Y
A
Y
K
N
N
M
A
S
W
Y
P
Zebra Danio
Brachydanio rerio
NP_001082825
603
66722
Q558
I
V
D
H
A
Y
K
Q
G
I
A
S
W
Y
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395280
537
59737
N473
N
E
D
L
E
K
G
N
L
Y
P
P
L
Q
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780686
581
64710
E534
K
I
A
V
R
V
G
E
Y
A
Y
D
T
G
M
Poplar Tree
Populus trichocarpa
P34105
591
65205
L536
E
E
Y
L
A
K
G
L
I
Y
P
P
L
S
N
Maize
Zea mays
P16243
636
69805
S581
Q
D
N
F
E
K
G
S
I
F
P
P
F
T
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.3
95
82.6
N.A.
89.3
90.3
N.A.
79.3
75.8
68.8
68.4
N.A.
N.A.
57.6
N.A.
59.7
Protein Similarity:
100
74.4
97
86.5
N.A.
94.9
95.9
N.A.
89.3
88.4
80.5
82
N.A.
N.A.
73.4
N.A.
75.7
P-Site Identity:
100
100
100
100
N.A.
80
80
N.A.
46.6
6.6
20
13.3
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
20
20
20
N.A.
N.A.
26.6
N.A.
20
Percent
Protein Identity:
48
44
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
65.4
61
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
40
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
65
0
22
8
0
0
50
8
15
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
50
22
0
0
0
0
0
0
0
0
8
0
0
8
% D
% Glu:
15
22
0
8
22
43
0
8
0
0
0
0
0
50
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
8
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
29
0
8
0
0
0
0
8
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
15
15
0
0
0
0
0
0
15
8
8
0
0
0
0
% I
% Lys:
36
0
0
0
15
29
58
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
15
0
0
0
15
8
0
0
0
15
0
0
% L
% Met:
0
0
0
0
0
0
0
15
0
8
0
0
0
0
8
% M
% Asn:
8
0
8
0
0
0
8
15
15
8
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
22
22
50
0
65
% P
% Gln:
22
0
0
0
36
0
0
8
0
0
0
0
0
8
0
% Q
% Arg:
8
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
8
0
8
0
15
0
8
8
% S
% Thr:
0
0
0
0
0
0
0
29
0
43
8
0
15
15
0
% T
% Val:
0
15
0
8
0
8
0
0
0
0
43
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% W
% Tyr:
0
0
8
58
0
15
8
0
8
15
8
43
0
15
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _