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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GJA8 All Species: 20.91
Human Site: S403 Identified Species: 51.11
UniProt: P48165 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48165 NP_005258.2 433 48229 S403 L P A E K T P S L C P E L T T
Chimpanzee Pan troglodytes XP_524857 433 48312 S403 L P A E K T P S L C P E L T T
Rhesus Macaque Macaca mulatta XP_001095298 435 48589 S405 L P A E K T P S L C Q E L T T
Dog Lupus familis XP_540274 439 48960 S409 L P A E K S P S L C P D L T R
Cat Felis silvestris
Mouse Mus musculus P28236 440 49579 S410 L S A E K A P S L C P E L T T
Rat Rattus norvegicus Q8K4Q9 440 49383 T410 L S A E K A P T L C P E L T T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516993 294 32753 V265 M L R V A H E V T P H P H P E
Chicken Gallus gallus P36381 400 45598 P370 V S D E V E G P S A P A E L A
Frog Xenopus laevis P51914 352 40615 A323 L G H Y S L S A F L P V S P K
Zebra Danio Brachydanio rerio O57474 381 43436 L352 K L T P G H E L Q P L A L I D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 94.9 87.9 N.A. 87.2 87.2 N.A. 51 72 38.5 41.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.3 96.3 92.2 N.A. 91.5 91.8 N.A. 57 79.4 54.2 56.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 80 N.A. 86.6 80 N.A. 0 13.3 13.3 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 93.3 N.A. 86.6 86.6 N.A. 6.6 20 20 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 60 0 10 20 0 10 0 10 0 20 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 60 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 10 % D
% Glu: 0 0 0 70 0 10 20 0 0 0 0 50 10 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 10 0 10 0 0 0 0 0 0 0 0 % G
% His: 0 0 10 0 0 20 0 0 0 0 10 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 10 0 0 0 60 0 0 0 0 0 0 0 0 0 10 % K
% Leu: 70 20 0 0 0 10 0 10 60 10 10 0 70 10 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 40 0 10 0 0 60 10 0 20 70 10 0 20 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % Q
% Arg: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % R
% Ser: 0 30 0 0 10 10 10 50 10 0 0 0 10 0 0 % S
% Thr: 0 0 10 0 0 30 0 10 10 0 0 0 0 60 50 % T
% Val: 10 0 0 10 10 0 0 10 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _