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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GABRA4
All Species:
16.36
Human Site:
S500
Identified Species:
45
UniProt:
P48169
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48169
NP_000800.2
554
61623
S500
I
G
A
T
G
K
L
S
A
T
P
P
P
S
A
Chimpanzee
Pan troglodytes
XP_001144345
453
50886
S399
T
R
A
P
I
L
Q
S
T
P
V
T
P
P
P
Rhesus Macaque
Macaca mulatta
XP_001101231
554
61478
S500
I
G
A
T
G
K
L
S
A
T
P
P
P
S
A
Dog
Lupus familis
XP_539251
545
60385
S491
I
G
A
S
G
K
L
S
A
T
T
P
P
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D6F4
552
60860
S498
T
G
A
A
G
N
V
S
A
T
P
P
P
P
A
Rat
Rattus norvegicus
P28471
552
60933
S498
T
G
V
P
G
N
V
S
A
T
P
P
P
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505750
451
50878
Q398
S
T
I
V
P
N
S
Q
S
A
S
T
T
P
P
Chicken
Gallus gallus
Q90845
465
51699
P412
P
A
P
P
A
P
P
P
V
G
G
T
S
K
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001017822
557
61444
K502
G
P
K
L
E
N
I
K
K
K
E
A
K
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.9
98.5
83.9
N.A.
90.6
89.3
N.A.
61.9
62.8
N.A.
66.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
71.3
98.9
87.5
N.A.
93.8
92.7
N.A.
72.1
71.6
N.A.
76.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
100
86.6
N.A.
66.6
66.6
N.A.
0
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
93.3
N.A.
73.3
73.3
N.A.
6.6
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
56
12
12
0
0
0
56
12
0
12
0
12
56
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
12
0
0
0
0
0
12
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
56
0
0
56
0
0
0
0
12
12
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
34
0
12
0
12
0
12
0
0
0
0
0
0
0
12
% I
% Lys:
0
0
12
0
0
34
0
12
12
12
0
0
12
12
0
% K
% Leu:
0
0
0
12
0
12
34
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
45
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
12
12
34
12
12
12
12
0
12
45
56
67
34
23
% P
% Gln:
0
0
0
0
0
0
12
12
0
0
0
0
0
0
12
% Q
% Arg:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
12
0
0
12
0
0
12
67
12
0
12
0
12
45
0
% S
% Thr:
34
12
0
23
0
0
0
0
12
56
12
34
12
0
0
% T
% Val:
0
0
12
12
0
0
23
0
12
0
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _