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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IREB2 All Species: 20.3
Human Site: T410 Identified Species: 31.9
UniProt: P48200 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48200 NP_004127.1 963 105047 T410 A K L E S M E T Y L K A V K L
Chimpanzee Pan troglodytes XP_523125 963 104993 T410 A K L E S M E T Y L K A V K L
Rhesus Macaque Macaca mulatta XP_001107837 964 105069 T411 A K L E S M E T Y L K A V K L
Dog Lupus familis XP_532364 964 105327 T411 A K L K S V E T Y L K A V K L
Cat Felis silvestris
Mouse Mus musculus Q811J3 963 104918 K411 T K L E S M E K Y L K A V K L
Rat Rattus norvegicus Q62751 963 104783 E411 T K L E S M E E Y L K A V K L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513243 1011 110449 T458 A K L E S V E T Y L K A V K L
Chicken Gallus gallus Q5ZLQ4 965 105344 A412 A K L E V M E A Y L K A V K L
Frog Xenopus laevis Q6NTP2 955 104418 N404 Q C V K T F E N Y L K A V K L
Zebra Danio Brachydanio rerio XP_001341791 896 98752 S371 E V I E M N L S S I V P H V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524303 899 98560 D371 F T Q S I T L D L S T V V T S
Honey Bee Apis mellifera XP_392993 890 98796 S371 D L G T V V S S V S G P K R P
Nematode Worm Caenorhab. elegans Q23500 887 96642 P372 V V P S V S G P K R P H D R V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42560 898 98134 H381 V S G P K R P H D R V P L K E
Baker's Yeast Sacchar. cerevisiae P19414 778 85350 D266 K I V E Y F G D G V D T F S A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.1 92.5 N.A. 93.6 93.8 N.A. 84.4 82.1 68.5 62.9 N.A. 54.5 55.5 52.3 N.A.
Protein Similarity: 100 99.6 99.6 96.8 N.A. 96.6 97.1 N.A. 89.9 91.1 81 77 N.A. 72.4 71.8 67.5 N.A.
P-Site Identity: 100 100 100 86.6 N.A. 86.6 86.6 N.A. 93.3 86.6 53.3 6.6 N.A. 6.6 0 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 86.6 86.6 N.A. 100 86.6 73.3 26.6 N.A. 6.6 20 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 49.1 26 N.A.
Protein Similarity: N.A. N.A. N.A. 65.5 42.8 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 40 0 0 0 0 0 0 7 0 0 0 60 0 0 7 % A
% Cys: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 0 0 14 7 0 7 0 7 0 0 % D
% Glu: 7 0 0 60 0 0 60 7 0 0 0 0 0 0 7 % E
% Phe: 7 0 0 0 0 14 0 0 0 0 0 0 7 0 0 % F
% Gly: 0 0 14 0 0 0 14 0 7 0 7 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 7 0 0 0 7 7 0 0 % H
% Ile: 0 7 7 0 7 0 0 0 0 7 0 0 0 0 0 % I
% Lys: 7 54 0 14 7 0 0 7 7 0 60 0 7 67 0 % K
% Leu: 0 7 54 0 0 0 14 0 7 60 0 0 7 0 60 % L
% Met: 0 0 0 0 7 40 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 7 0 7 0 0 0 0 0 0 0 % N
% Pro: 0 0 7 7 0 0 7 7 0 0 7 20 0 0 7 % P
% Gln: 7 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 7 0 0 0 14 0 0 0 14 0 % R
% Ser: 0 7 0 14 47 7 7 14 7 14 0 0 0 7 14 % S
% Thr: 14 7 0 7 7 7 0 34 0 0 7 7 0 7 0 % T
% Val: 14 14 14 0 20 20 0 0 7 7 14 7 67 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 0 60 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _