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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IREB2
All Species:
19.7
Human Site:
T458
Identified Species:
30.95
UniProt:
P48200
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48200
NP_004127.1
963
105047
T458
P
Q
D
R
V
A
V
T
D
M
K
S
D
F
Q
Chimpanzee
Pan troglodytes
XP_523125
963
104993
T458
P
Q
D
R
V
A
V
T
D
M
K
S
D
F
Q
Rhesus Macaque
Macaca mulatta
XP_001107837
964
105069
T459
P
Q
D
R
V
A
V
T
D
M
K
S
D
F
Q
Dog
Lupus familis
XP_532364
964
105327
T459
P
Q
D
R
V
A
V
T
D
M
K
R
D
F
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q811J3
963
104918
D459
Q
D
R
V
A
V
T
D
M
K
S
D
F
Q
A
Rat
Rattus norvegicus
Q62751
963
104783
D459
Q
D
R
V
A
V
T
D
M
K
S
D
F
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513243
1011
110449
T506
P
Q
D
R
V
A
V
T
D
M
K
R
D
F
Q
Chicken
Gallus gallus
Q5ZLQ4
965
105344
N460
S
Q
D
R
V
A
V
N
N
M
K
S
D
F
Q
Frog
Xenopus laevis
Q6NTP2
955
104418
M452
D
R
I
S
V
M
D
M
K
K
D
F
E
T
C
Zebra Danio
Brachydanio rerio
XP_001341791
896
98752
L419
S
K
E
K
Q
S
T
L
V
P
F
R
H
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524303
899
98560
S419
A
I
A
P
E
A
Q
S
A
F
G
E
F
Q
W
Honey Bee
Apis mellifera
XP_392993
890
98796
Y419
D
T
V
G
L
F
E
Y
E
G
K
D
Y
K
L
Nematode Worm
Caenorhab. elegans
Q23500
887
96642
T420
T
I
T
N
H
G
R
T
A
E
L
T
H
G
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42560
898
98134
R429
N
G
T
T
A
Q
L
R
H
G
D
V
V
I
A
Baker's Yeast
Sacchar. cerevisiae
P19414
778
85350
F314
G
R
G
K
I
A
D
F
A
K
L
Y
H
K
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.1
92.5
N.A.
93.6
93.8
N.A.
84.4
82.1
68.5
62.9
N.A.
54.5
55.5
52.3
N.A.
Protein Similarity:
100
99.6
99.6
96.8
N.A.
96.6
97.1
N.A.
89.9
91.1
81
77
N.A.
72.4
71.8
67.5
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
0
0
N.A.
93.3
80
6.6
0
N.A.
6.6
6.6
6.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
0
0
N.A.
93.3
86.6
20
26.6
N.A.
13.3
20
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.1
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.5
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
20
54
0
0
20
0
0
0
0
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
14
14
40
0
0
0
14
14
34
0
14
20
40
7
7
% D
% Glu:
0
0
7
0
7
0
7
0
7
7
0
7
7
0
0
% E
% Phe:
0
0
0
0
0
7
0
7
0
7
7
7
20
40
0
% F
% Gly:
7
7
7
7
0
7
0
0
0
14
7
0
0
7
7
% G
% His:
0
0
0
0
7
0
0
0
7
0
0
0
20
0
0
% H
% Ile:
0
14
7
0
7
0
0
0
0
0
0
0
0
7
0
% I
% Lys:
0
7
0
14
0
0
0
0
7
27
47
0
0
14
0
% K
% Leu:
0
0
0
0
7
0
7
7
0
0
14
0
0
0
7
% L
% Met:
0
0
0
0
0
7
0
7
14
40
0
0
0
0
0
% M
% Asn:
7
0
0
7
0
0
0
7
7
0
0
0
0
0
0
% N
% Pro:
34
0
0
7
0
0
0
0
0
7
0
0
0
0
0
% P
% Gln:
14
40
0
0
7
7
7
0
0
0
0
0
0
20
40
% Q
% Arg:
0
14
14
40
0
0
7
7
0
0
0
20
0
0
0
% R
% Ser:
14
0
0
7
0
7
0
7
0
0
14
27
0
0
7
% S
% Thr:
7
7
14
7
0
0
20
40
0
0
0
7
0
7
0
% T
% Val:
0
0
7
14
47
14
40
0
7
0
0
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
0
0
0
0
0
0
0
7
0
0
0
7
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _