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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IREB2 All Species: 13.64
Human Site: T909 Identified Species: 21.43
UniProt: P48200 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48200 NP_004127.1 963 105047 T909 L G L S G R E T F S L T F P E
Chimpanzee Pan troglodytes XP_523125 963 104993 T909 L G L S G R E T F S L T F P E
Rhesus Macaque Macaca mulatta XP_001107837 964 105069 T910 L G L S G R E T F S L T F P E
Dog Lupus familis XP_532364 964 105327 T910 L G L S G R E T F S L T F P E
Cat Felis silvestris
Mouse Mus musculus Q811J3 963 104918 V909 L G L S G R E V F S L S F P E
Rat Rattus norvegicus Q62751 963 104783 V909 L G L S G R E V F S L S F P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513243 1011 110449 Q957 L G L T G K E Q F S L T F P E
Chicken Gallus gallus Q5ZLQ4 965 105344 Q911 L G L T G R E Q F S I L F P P
Frog Xenopus laevis Q6NTP2 955 104418 Q901 L G L S G K E Q Y S L S L P V
Zebra Danio Brachydanio rerio XP_001341791 896 98752 R841 L E L C G K E R F T I D I P E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524303 899 98560 V844 L N L T G R E V Y N I A L P E
Honey Bee Apis mellifera XP_392993 890 98796 V836 L G L T G Y E V Y D I S I S E
Nematode Worm Caenorhab. elegans Q23500 887 96642 Q832 L G L T G K E Q F S I G V P D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42560 898 98134 I842 T G Q E L Y T I E L P N N V S
Baker's Yeast Sacchar. cerevisiae P19414 778 85350 G725 D D R I D I L G L A E L A P G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.1 92.5 N.A. 93.6 93.8 N.A. 84.4 82.1 68.5 62.9 N.A. 54.5 55.5 52.3 N.A.
Protein Similarity: 100 99.6 99.6 96.8 N.A. 96.6 97.1 N.A. 89.9 91.1 81 77 N.A. 72.4 71.8 67.5 N.A.
P-Site Identity: 100 100 100 100 N.A. 86.6 86.6 N.A. 80 66.6 60 46.6 N.A. 46.6 40 53.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 93.3 80 80 66.6 N.A. 73.3 66.6 80 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 49.1 26 N.A.
Protein Similarity: N.A. N.A. N.A. 65.5 42.8 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 7 0 7 7 0 0 % A
% Cys: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 7 0 0 7 0 0 0 0 7 0 7 0 0 7 % D
% Glu: 0 7 0 7 0 0 87 0 7 0 7 0 0 0 67 % E
% Phe: 0 0 0 0 0 0 0 0 67 0 0 0 54 0 0 % F
% Gly: 0 80 0 0 87 0 0 7 0 0 0 7 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 0 7 0 7 0 0 34 0 14 0 0 % I
% Lys: 0 0 0 0 0 27 0 0 0 0 0 0 0 0 0 % K
% Leu: 87 0 87 0 7 0 7 0 7 7 54 14 14 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 0 0 0 0 0 7 0 7 7 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 7 0 0 87 7 % P
% Gln: 0 0 7 0 0 0 0 27 0 0 0 0 0 0 0 % Q
% Arg: 0 0 7 0 0 54 0 7 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 47 0 0 0 0 0 67 0 27 0 7 7 % S
% Thr: 7 0 0 34 0 0 7 27 0 7 0 34 0 0 0 % T
% Val: 0 0 0 0 0 0 0 27 0 0 0 0 7 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 14 0 0 20 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _