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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM4SF4
All Species:
21.52
Human Site:
Y136
Identified Species:
59.17
UniProt:
P48230
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48230
NP_004608.1
202
21396
Y136
Y
P
F
H
D
G
D
Y
L
N
D
E
A
L
W
Chimpanzee
Pan troglodytes
XP_001140185
239
25958
G137
Y
T
F
A
S
T
E
G
Q
Y
L
L
D
T
S
Rhesus Macaque
Macaca mulatta
XP_001108653
202
21326
Y136
Y
P
F
H
D
G
D
Y
L
N
D
K
A
L
W
Dog
Lupus familis
XP_854442
202
21494
Y136
Y
P
F
H
D
G
D
Y
L
N
D
E
A
L
W
Cat
Felis silvestris
Mouse
Mus musculus
Q91XD3
202
21277
Y136
Y
P
F
H
D
G
D
Y
L
K
D
Q
A
L
W
Rat
Rattus norvegicus
Q9EQL5
202
21466
Y136
Y
P
F
H
D
G
D
Y
L
N
D
Q
A
L
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509686
203
21529
N136
N
Y
P
F
L
H
G
N
Y
L
S
D
R
S
L
Chicken
Gallus gallus
XP_001234023
201
21199
L136
P
F
K
D
G
D
Y
L
S
D
Q
K
M
W
D
Frog
Xenopus laevis
NP_001089624
202
21013
Y136
Y
P
F
H
D
G
N
Y
L
G
N
T
D
M
W
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.5
94
89.5
N.A.
87.6
87.6
N.A.
73.4
72.2
72.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
60.2
97.5
95.5
N.A.
95
94
N.A.
84.2
84.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
93.3
100
N.A.
86.6
93.3
N.A.
0
0
60
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
93.3
100
N.A.
6.6
13.3
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
0
0
0
0
0
0
0
56
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
67
12
56
0
0
12
56
12
23
0
12
% D
% Glu:
0
0
0
0
0
0
12
0
0
0
0
23
0
0
0
% E
% Phe:
0
12
78
12
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
12
67
12
12
0
12
0
0
0
0
0
% G
% His:
0
0
0
67
0
12
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
12
0
0
0
0
0
0
12
0
23
0
0
0
% K
% Leu:
0
0
0
0
12
0
0
12
67
12
12
12
0
56
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
12
12
0
% M
% Asn:
12
0
0
0
0
0
12
12
0
45
12
0
0
0
0
% N
% Pro:
12
67
12
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
12
0
12
23
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% R
% Ser:
0
0
0
0
12
0
0
0
12
0
12
0
0
12
12
% S
% Thr:
0
12
0
0
0
12
0
0
0
0
0
12
0
12
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
67
% W
% Tyr:
78
12
0
0
0
0
12
67
12
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _