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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFX3
All Species:
24.55
Human Site:
S178
Identified Species:
60
UniProt:
P48380
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48380
NP_002910.1
749
83530
S178
G
L
S
T
H
R
S
S
L
L
N
S
H
L
Q
Chimpanzee
Pan troglodytes
XP_520464
739
82471
S177
D
G
L
S
T
H
R
S
S
L
L
N
S
H
L
Rhesus Macaque
Macaca mulatta
XP_001086729
749
83538
S178
G
L
S
T
H
R
S
S
L
L
N
S
H
L
Q
Dog
Lupus familis
XP_533540
749
83490
S178
G
L
S
T
H
R
S
S
L
L
N
S
H
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
P48381
749
83493
S178
G
L
S
T
H
R
S
S
L
L
N
S
H
L
Q
Rat
Rattus norvegicus
B2GV50
692
76518
T131
S
H
G
M
V
G
I
T
M
D
V
S
G
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506894
797
89464
S227
G
L
S
T
H
R
S
S
L
L
N
S
H
L
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
Q32NR3
694
77765
E133
Y
L
I
H
G
G
L
E
N
S
R
H
T
P
S
Zebra Danio
Brachydanio rerio
A0JMF8
765
84529
S184
G
L
S
S
Q
R
S
S
L
L
N
S
H
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09555
805
90889
I190
E
E
F
D
Y
N
Q
I
E
Y
G
N
A
V
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.9
99.8
99.4
N.A.
98.9
59.9
N.A.
84.4
N.A.
66.2
75.5
N.A.
N.A.
N.A.
28.8
N.A.
Protein Similarity:
100
96.8
100
99.7
N.A.
99.4
71.3
N.A.
88.5
N.A.
77.4
84.3
N.A.
N.A.
N.A.
49
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
100
6.6
N.A.
100
N.A.
6.6
86.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
100
20
N.A.
100
N.A.
6.6
93.3
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
10
10
0
0
0
0
0
10
10
0
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
60
10
10
0
10
20
0
0
0
0
10
0
10
0
0
% G
% His:
0
10
0
10
50
10
0
0
0
0
0
10
60
10
0
% H
% Ile:
0
0
10
0
0
0
10
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
70
10
0
0
0
10
0
60
70
10
0
0
60
10
% L
% Met:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
10
0
60
20
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% P
% Gln:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
60
% Q
% Arg:
0
0
0
0
0
60
10
0
0
0
10
0
0
0
0
% R
% Ser:
10
0
60
20
0
0
60
70
10
10
0
70
10
0
10
% S
% Thr:
0
0
0
50
10
0
0
10
0
0
0
0
10
10
10
% T
% Val:
0
0
0
0
10
0
0
0
0
0
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _