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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFX3
All Species:
23.33
Human Site:
S260
Identified Species:
57.04
UniProt:
P48380
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48380
NP_002910.1
749
83530
S260
G
I
R
V
K
P
D
S
P
L
N
R
L
Q
E
Chimpanzee
Pan troglodytes
XP_520464
739
82471
P258
Y
Y
G
I
R
V
K
P
D
S
P
L
N
R
L
Rhesus Macaque
Macaca mulatta
XP_001086729
749
83538
S260
G
I
R
V
K
P
D
S
P
L
N
R
L
Q
E
Dog
Lupus familis
XP_533540
749
83490
S260
G
I
R
V
K
P
D
S
P
L
N
R
L
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
P48381
749
83493
S260
G
I
R
V
K
P
D
S
P
L
N
R
L
Q
E
Rat
Rattus norvegicus
B2GV50
692
76518
G212
P
V
N
A
A
S
F
G
K
L
I
R
S
V
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506894
797
89464
S309
G
I
R
V
K
P
D
S
P
L
N
R
L
Q
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Q32NR3
694
77765
A214
K
L
D
P
V
N
A
A
S
F
G
K
L
I
R
Zebra Danio
Brachydanio rerio
A0JMF8
765
84529
S266
G
I
R
V
K
P
D
S
P
L
N
R
L
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09555
805
90889
S274
N
Y
E
I
G
E
G
S
L
P
R
C
E
L
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.9
99.8
99.4
N.A.
98.9
59.9
N.A.
84.4
N.A.
66.2
75.5
N.A.
N.A.
N.A.
28.8
N.A.
Protein Similarity:
100
96.8
100
99.7
N.A.
99.4
71.3
N.A.
88.5
N.A.
77.4
84.3
N.A.
N.A.
N.A.
49
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
13.3
N.A.
100
N.A.
6.6
100
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
20
N.A.
100
N.A.
26.6
100
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
0
10
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
10
0
0
0
60
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
0
10
0
0
0
0
0
0
10
0
60
% E
% Phe:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
10
% F
% Gly:
60
0
10
0
10
0
10
10
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
60
0
20
0
0
0
0
0
0
10
0
0
10
0
% I
% Lys:
10
0
0
0
60
0
10
0
10
0
0
10
0
0
0
% K
% Leu:
0
10
0
0
0
0
0
0
10
70
0
10
70
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
10
0
0
10
0
0
0
0
60
0
10
0
0
% N
% Pro:
10
0
0
10
0
60
0
10
60
10
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
60
0
% Q
% Arg:
0
0
60
0
10
0
0
0
0
0
10
70
0
10
10
% R
% Ser:
0
0
0
0
0
10
0
70
10
10
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
0
60
10
10
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
20
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _