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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RFX5 All Species: 10
Human Site: S496 Identified Species: 24.44
UniProt: P48382 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48382 NP_000440.1 616 65323 S496 A M E S A Q S S R L P W E T W
Chimpanzee Pan troglodytes XP_001171715 616 65363 S496 A M E S A Q S S R L P W E T W
Rhesus Macaque Macaca mulatta XP_001106865 620 65899 R501 A M D S A Q S R L P W E T W G
Dog Lupus familis XP_540315 619 65859 S500 A M D S A P S S R L P R E T W
Cat Felis silvestris
Mouse Mus musculus NP_059091 658 69716 P539 I V N S P R S P R L L W E T W
Rat Rattus norvegicus NP_001101164 681 71517 P562 A V N S P R S P R L L W E T W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514248 1500 157497 P1338 A A F S G A N P Q G L I H S G
Chicken Gallus gallus XP_423395 935 101039 D828 G D A A E G T D L G A E R C D
Frog Xenopus laevis NP_001084673 254 28561 G147 A R R L G G R G Q S K Y P F Y
Zebra Danio Brachydanio rerio XP_690961 584 63748 S457 S C P P A A P S Q L V E I V I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 96.1 85.4 N.A. 72.1 71.8 N.A. 21.6 20 24.1 32.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 97 89.1 N.A. 76.9 76.2 N.A. 29.5 30.7 30.8 47.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 40 80 N.A. 53.3 60 N.A. 13.3 0 6.6 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 46.6 86.6 N.A. 66.6 73.3 N.A. 33.3 13.3 26.6 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 70 10 10 10 50 20 0 0 0 0 10 0 0 0 0 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 10 20 0 0 0 0 10 0 0 0 0 0 0 10 % D
% Glu: 0 0 20 0 10 0 0 0 0 0 0 30 50 0 0 % E
% Phe: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 10 0 0 0 20 20 0 10 0 20 0 0 0 0 20 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 10 10 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % K
% Leu: 0 0 0 10 0 0 0 0 20 60 30 0 0 0 0 % L
% Met: 0 40 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 20 0 0 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 10 20 10 10 30 0 10 30 0 10 0 0 % P
% Gln: 0 0 0 0 0 30 0 0 30 0 0 0 0 0 0 % Q
% Arg: 0 10 10 0 0 20 10 10 50 0 0 10 10 0 0 % R
% Ser: 10 0 0 70 0 0 60 40 0 10 0 0 0 10 0 % S
% Thr: 0 0 0 0 0 0 10 0 0 0 0 0 10 50 0 % T
% Val: 0 20 0 0 0 0 0 0 0 0 10 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 40 0 10 50 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _