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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RFX5 All Species: 14.24
Human Site: S505 Identified Species: 34.81
UniProt: P48382 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48382 NP_000440.1 616 65323 S505 L P W E T W G S G G E G N S A
Chimpanzee Pan troglodytes XP_001171715 616 65363 S505 L P W E T W G S G G E G N S A
Rhesus Macaque Macaca mulatta XP_001106865 620 65899 G510 P W E T W G L G G E G N S A G
Dog Lupus familis XP_540315 619 65859 S509 L P R E T W A S G V G S S S A
Cat Felis silvestris
Mouse Mus musculus NP_059091 658 69716 S548 L L W E T W G S K R E N N F I
Rat Rattus norvegicus NP_001101164 681 71517 S571 L L W E T W G S K R E N N L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514248 1500 157497 S1347 G L I H S G A S L Y E F P T P
Chicken Gallus gallus XP_423395 935 101039 A837 G A E R C D S A H G G D S G H
Frog Xenopus laevis NP_001084673 254 28561 G156 S K Y P F Y M G G A S M L H S
Zebra Danio Brachydanio rerio XP_690961 584 63748 D466 L V E I V I Q D Q Q S L M L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 96.1 85.4 N.A. 72.1 71.8 N.A. 21.6 20 24.1 32.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 97 89.1 N.A. 76.9 76.2 N.A. 29.5 30.7 30.8 47.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 60 N.A. 60 60 N.A. 13.3 6.6 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 20 66.6 N.A. 60 60 N.A. 26.6 20 26.6 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 20 10 0 10 0 0 0 10 30 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 10 0 0 0 10 0 0 0 % D
% Glu: 0 0 30 50 0 0 0 0 0 10 50 0 0 0 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 10 0 10 0 % F
% Gly: 20 0 0 0 0 20 40 20 50 30 30 20 0 10 10 % G
% His: 0 0 0 10 0 0 0 0 10 0 0 0 0 10 10 % H
% Ile: 0 0 10 10 0 10 0 0 0 0 0 0 0 0 10 % I
% Lys: 0 10 0 0 0 0 0 0 20 0 0 0 0 0 0 % K
% Leu: 60 30 0 0 0 0 10 0 10 0 0 10 10 20 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 10 10 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 30 40 0 0 % N
% Pro: 10 30 0 10 0 0 0 0 0 0 0 0 10 0 10 % P
% Gln: 0 0 0 0 0 0 10 0 10 10 0 0 0 0 0 % Q
% Arg: 0 0 10 10 0 0 0 0 0 20 0 0 0 0 0 % R
% Ser: 10 0 0 0 10 0 10 60 0 0 20 10 30 30 20 % S
% Thr: 0 0 0 10 50 0 0 0 0 0 0 0 0 10 0 % T
% Val: 0 10 0 0 10 0 0 0 0 10 0 0 0 0 10 % V
% Trp: 0 10 40 0 10 50 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 10 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _