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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFX5
All Species:
11.52
Human Site:
S548
Identified Species:
28.15
UniProt:
P48382
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48382
NP_000440.1
616
65323
S548
K
G
G
R
G
P
G
S
Q
H
T
K
E
A
E
Chimpanzee
Pan troglodytes
XP_001171715
616
65363
S548
K
G
G
R
G
P
G
S
R
H
T
K
E
A
E
Rhesus Macaque
Macaca mulatta
XP_001106865
620
65899
S552
K
G
G
R
G
P
S
S
R
H
T
K
E
A
E
Dog
Lupus familis
XP_540315
619
65859
A552
K
G
G
R
G
P
S
A
Q
H
A
K
E
A
E
Cat
Felis silvestris
Mouse
Mus musculus
NP_059091
658
69716
S590
S
K
G
E
R
S
L
S
S
Q
E
A
K
E
A
Rat
Rattus norvegicus
NP_001101164
681
71517
S613
S
K
G
E
K
S
L
S
S
Q
E
A
K
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514248
1500
157497
S1428
S
S
E
I
R
L
S
S
E
L
S
G
S
I
N
Chicken
Gallus gallus
XP_423395
935
101039
D868
A
H
G
G
D
I
T
D
G
A
A
V
V
S
P
Frog
Xenopus laevis
NP_001084673
254
28561
K187
N
N
E
G
V
T
Y
K
T
A
V
Q
I
K
R
Zebra Danio
Brachydanio rerio
XP_690961
584
63748
P497
V
V
Q
C
H
P
A
P
E
A
E
K
Q
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.1
85.4
N.A.
72.1
71.8
N.A.
21.6
20
24.1
32.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
97
89.1
N.A.
76.9
76.2
N.A.
29.5
30.7
30.8
47.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
86.6
80
N.A.
13.3
13.3
N.A.
6.6
6.6
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
20
20
N.A.
20
13.3
6.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
10
10
0
30
20
20
0
40
20
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
20
20
0
0
0
0
20
0
30
0
40
20
40
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
40
70
20
40
0
20
0
10
0
0
10
0
0
0
% G
% His:
0
10
0
0
10
0
0
0
0
40
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
10
0
0
0
0
0
0
10
10
0
% I
% Lys:
40
20
0
0
10
0
0
10
0
0
0
50
20
10
0
% K
% Leu:
0
0
0
0
0
10
20
0
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
50
0
10
0
0
0
0
0
0
10
% P
% Gln:
0
0
10
0
0
0
0
0
20
20
0
10
10
10
0
% Q
% Arg:
0
0
0
40
20
0
0
0
20
0
0
0
0
0
10
% R
% Ser:
30
10
0
0
0
20
30
60
20
0
10
0
10
10
10
% S
% Thr:
0
0
0
0
0
10
10
0
10
0
30
0
0
0
0
% T
% Val:
10
10
0
0
10
0
0
0
0
0
10
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _