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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIP4K2A All Species: 9.09
Human Site: S347 Identified Species: 20
UniProt: P48426 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48426 NP_005019.2 406 46225 S347 G I K C H E N S P R K E V Y F
Chimpanzee Pan troglodytes XP_001145662 380 43525 S321 G I K C H E N S P R K E V Y F
Rhesus Macaque Macaca mulatta XP_001099389 382 43672 S323 G I K C H E N S P R K E V Y F
Dog Lupus familis XP_548154 416 47327 A357 A M K S H E S A P K K E V Y F
Cat Felis silvestris
Mouse Mus musculus O70172 405 46133 A347 A I K C H E N A P R K E V Y F
Rat Rattus norvegicus Q9R0I8 406 46191 A347 A I K C H E N A P R K E V Y F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510625 479 54696 A416 G I K C H E N A P R K E V Y F
Chicken Gallus gallus Q5F356 405 46073 A346 G I K S H E S A P R K E V Y F
Frog Xenopus laevis Q5PQ01 419 47633 A360 A I K S S D N A P Q K E V Y F
Zebra Danio Brachydanio rerio Q6IQE1 416 47361 A357 A V K S A P G A P Q R E V Y F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392797 416 47916 A356 A I P S K E G A P T K E I Y F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.1 89.9 75.9 N.A. 98 97.5 N.A. 76.8 93.3 67.3 64.6 N.A. N.A. 59.6 N.A. N.A.
Protein Similarity: 100 91.6 90.3 87.2 N.A. 99.2 99.2 N.A. 79.3 97 79.7 77.8 N.A. N.A. 73.3 N.A. N.A.
P-Site Identity: 100 100 100 60 N.A. 86.6 86.6 N.A. 93.3 80 60 40 N.A. N.A. 46.6 N.A. N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. 100 93.3 80 66.6 N.A. N.A. 60 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 55 0 0 0 10 0 0 73 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 55 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 82 0 0 0 0 0 100 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % F
% Gly: 46 0 0 0 0 0 19 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 73 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 82 0 0 0 0 0 0 0 0 0 0 10 0 0 % I
% Lys: 0 0 91 0 10 0 0 0 0 10 91 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 64 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 0 0 10 0 0 100 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 64 10 0 0 0 0 % R
% Ser: 0 0 0 46 10 0 19 28 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % T
% Val: 0 10 0 0 0 0 0 0 0 0 0 0 91 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _