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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOX2
All Species:
31.82
Human Site:
Y125
Identified Species:
87.5
UniProt:
P48431
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48431
NP_003097.1
317
34310
Y125
T
L
M
K
K
D
K
Y
T
L
P
G
G
L
L
Chimpanzee
Pan troglodytes
XP_516895
690
75569
Y266
T
L
M
K
K
D
K
Y
T
L
P
G
G
L
L
Rhesus Macaque
Macaca mulatta
NP_001136412
319
34405
Y127
T
L
M
K
K
D
K
Y
T
L
P
G
G
L
L
Dog
Lupus familis
XP_545216
489
52561
Y297
T
L
M
K
K
D
K
Y
T
L
P
G
G
L
L
Cat
Felis silvestris
Mouse
Mus musculus
P48432
319
34436
Y127
T
L
M
K
K
D
K
Y
T
L
P
G
G
L
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506984
290
31501
P107
L
P
G
G
L
L
A
P
G
G
T
G
L
A
G
Chicken
Gallus gallus
P48430
315
34493
Y123
T
L
M
K
K
D
K
Y
T
L
P
G
G
L
L
Frog
Xenopus laevis
O42569
311
34087
Y121
T
L
M
K
K
D
K
Y
T
L
P
G
G
L
L
Zebra Danio
Brachydanio rerio
Q6P0E1
315
34680
Y122
T
L
M
K
K
D
K
Y
T
L
P
G
G
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.2
99.3
64.8
N.A.
96.2
N.A.
N.A.
86.1
93.3
87.6
87.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
45.2
99.3
64.8
N.A.
97.4
N.A.
N.A.
87.3
95.5
90.8
92.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
6.6
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
6.6
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
12
0
0
0
0
0
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
89
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
12
12
0
0
0
0
12
12
0
100
89
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
89
89
0
89
0
0
0
0
0
0
0
0
% K
% Leu:
12
89
0
0
12
12
0
0
0
89
0
0
12
89
89
% L
% Met:
0
0
89
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
12
0
0
0
0
0
12
0
0
89
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
89
0
0
0
0
0
0
0
89
0
12
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
89
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _