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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARCN1 All Species: 41.52
Human Site: S493 Identified Species: 60.89
UniProt: P48444 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48444 NP_001135753.1 511 57210 S493 V T Q V D G N S P V R F S T E
Chimpanzee Pan troglodytes XP_001161708 552 61638 S534 V T Q V D G N S P V R F S T E
Rhesus Macaque Macaca mulatta XP_001098493 511 57160 S493 V T Q V D G N S P V R F S T E
Dog Lupus familis XP_536552 511 57227 S493 V T Q V D G N S P V R F S T E
Cat Felis silvestris
Mouse Mus musculus Q5XJY5 511 57199 S493 V T Q V D G N S P V R F S T E
Rat Rattus norvegicus Q66H80 511 57181 S493 V T Q V D G N S P V R F S T E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516226 533 59394 S515 V T Q V E G N S P V R F S T E
Chicken Gallus gallus Q5ZL57 510 57152 S492 V T Q V D G N S P V R F S T E
Frog Xenopus laevis NP_001080683 513 57250 S495 V N Q V D G N S P V R Y S T E
Zebra Danio Brachydanio rerio NP_958867 509 56739 S491 V S Q V D G D S P V R Y S T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001162642 531 57799 E512 D V V Q V D S E A A V K Y S S
Honey Bee Apis mellifera XP_624725 515 57788 E496 E V L L V E D E S P V K Y S V
Nematode Worm Caenorhab. elegans Q09236 515 56628 P498 V V K N D G S P V T Y S V E T
Sea Urchin Strong. purpuratus XP_780010 519 57495 Q501 V L S V E S D Q P V K F S S D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q93Y22 527 57700 G507 M I P L R G G G G A T P R F V
Baker's Yeast Sacchar. cerevisiae P43621 546 60609 T513 D K L A K S F T G M A I Q S V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.5 99.4 98.8 N.A. 98.8 98.8 N.A. 91.9 94.7 87.1 82.5 N.A. 57.4 61.1 50.4 62.8
Protein Similarity: 100 92.5 100 100 N.A. 99.6 99.6 N.A. 94.9 97.8 94.5 91.9 N.A. 72.5 77.4 68.3 80.3
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 93.3 100 86.6 80 N.A. 0 0 20 40
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 93.3 100 N.A. 13.3 20 33.3 73.3
Percent
Protein Identity: N.A. N.A. N.A. 39.6 30.9 N.A.
Protein Similarity: N.A. N.A. N.A. 63.1 52.2 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 0 0 0 0 7 13 7 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 13 0 0 0 63 7 19 0 0 0 0 0 0 0 7 % D
% Glu: 7 0 0 0 13 7 0 13 0 0 0 0 0 7 63 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 0 57 0 7 0 % F
% Gly: 0 0 0 0 0 75 7 7 13 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 0 0 0 0 0 0 0 7 0 0 0 % I
% Lys: 0 7 7 0 7 0 0 0 0 0 7 13 0 0 0 % K
% Leu: 0 7 13 13 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 7 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % M
% Asn: 0 7 0 7 0 0 57 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 7 0 0 0 0 7 69 7 0 7 0 0 0 % P
% Gln: 0 0 63 7 0 0 0 7 0 0 0 0 7 0 0 % Q
% Arg: 0 0 0 0 7 0 0 0 0 0 63 0 7 0 0 % R
% Ser: 0 7 7 0 0 13 13 63 7 0 0 7 69 25 7 % S
% Thr: 0 50 0 0 0 0 0 7 0 7 7 0 0 63 7 % T
% Val: 75 19 7 69 13 0 0 0 7 69 13 0 7 0 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 7 13 13 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _