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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LSS
All Species:
20.3
Human Site:
T287
Identified Species:
37.22
UniProt:
P48449
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48449
NP_001001438.1
732
83309
T287
V
A
P
D
E
L
Y
T
P
H
S
W
L
L
R
Chimpanzee
Pan troglodytes
XP_001159379
732
83231
T287
V
A
P
D
E
L
Y
T
P
H
S
W
L
L
R
Rhesus Macaque
Macaca mulatta
XP_001098607
732
83143
T287
V
A
P
D
E
L
Y
T
P
H
S
W
L
L
H
Dog
Lupus familis
XP_548733
654
72679
R263
T
S
E
H
T
L
Q
R
P
E
R
V
L
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BLN5
733
83123
T288
V
S
P
D
E
M
Y
T
P
H
S
W
L
L
H
Rat
Rattus norvegicus
P48450
733
83282
T288
V
C
P
D
D
M
Y
T
P
H
S
W
L
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514164
568
63937
G177
L
V
R
W
Y
V
D
G
S
T
S
S
V
F
Q
Chicken
Gallus gallus
NP_001006514
676
76923
V282
S
P
A
F
Q
E
H
V
S
R
I
P
D
Y
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001077036
735
83649
T288
V
A
T
C
D
L
Y
T
P
H
S
N
L
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193804
671
77348
L274
I
S
K
V
I
Q
M
L
A
R
W
H
I
D
G
Poplar Tree
Populus trichocarpa
XP_002308131
761
86469
L318
D
L
Y
Y
P
H
P
L
V
Q
D
V
L
W
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38605
759
86015
L316
D
L
Y
Y
P
H
P
L
V
Q
D
I
L
W
A
Baker's Yeast
Sacchar. cerevisiae
P38604
731
83442
P290
C
G
V
D
L
Y
Y
P
H
S
T
T
L
N
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.4
47.8
N.A.
85.5
84.3
N.A.
57.3
69.8
N.A.
75.2
N.A.
N.A.
N.A.
N.A.
46.3
Protein Similarity:
100
99.4
99
59.9
N.A.
92.5
91.6
N.A.
64.6
78.4
N.A.
86.1
N.A.
N.A.
N.A.
N.A.
62.7
P-Site Identity:
100
100
93.3
20
N.A.
80
73.3
N.A.
6.6
0
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
33.3
N.A.
93.3
86.6
N.A.
33.3
13.3
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
44.2
N.A.
N.A.
44.4
40.8
N.A.
Protein Similarity:
60.3
N.A.
N.A.
61.1
58
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
31
8
0
0
0
0
0
8
0
0
0
0
0
24
% A
% Cys:
8
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
0
47
16
0
8
0
0
0
16
0
8
8
0
% D
% Glu:
0
0
8
0
31
8
0
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
8
% G
% His:
0
0
0
8
0
16
8
0
8
47
0
8
0
0
24
% H
% Ile:
8
0
0
0
8
0
0
0
0
0
8
8
8
0
8
% I
% Lys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
16
0
0
8
39
0
24
0
0
0
0
77
47
8
% L
% Met:
0
0
0
0
0
16
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% N
% Pro:
0
8
39
0
16
0
16
8
54
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
8
8
8
0
0
16
0
0
0
0
8
% Q
% Arg:
0
0
8
0
0
0
0
8
0
16
8
0
0
0
16
% R
% Ser:
8
24
0
0
0
0
0
0
16
8
54
8
0
0
0
% S
% Thr:
8
0
8
0
8
0
0
47
0
8
8
8
0
0
8
% T
% Val:
47
8
8
8
0
8
0
8
16
0
0
16
8
8
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
8
39
0
16
0
% W
% Tyr:
0
0
16
16
8
8
54
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _