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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP3CC
All Species:
42.42
Human Site:
S290
Identified Species:
66.67
UniProt:
P48454
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48454
NP_005596.2
512
58129
S290
G
Y
R
M
Y
R
K
S
Q
A
T
G
F
P
S
Chimpanzee
Pan troglodytes
XP_001155871
512
58132
S290
G
Y
R
M
Y
R
K
S
Q
A
T
G
F
P
S
Rhesus Macaque
Macaca mulatta
XP_001103623
511
58002
S290
G
Y
R
M
Y
R
K
S
Q
A
T
G
F
P
S
Dog
Lupus familis
XP_851300
592
66956
S348
G
Y
R
M
Y
R
K
S
Q
T
T
G
F
P
S
Cat
Felis silvestris
Mouse
Mus musculus
P48455
513
58681
N290
G
Y
R
M
Y
R
K
N
Q
A
T
G
F
P
S
Rat
Rattus norvegicus
P63329
521
58625
S294
G
Y
R
M
Y
R
K
S
Q
T
T
G
F
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517401
562
63623
S341
G
Y
R
M
Y
R
K
S
Q
T
T
G
F
P
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080813
518
58366
S294
G
Y
R
M
Y
R
K
S
Q
T
T
G
F
P
S
Zebra Danio
Brachydanio rerio
NP_001074063
506
57495
S291
G
Y
R
M
Y
R
K
S
Q
T
T
G
F
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27889
570
63082
S360
G
Y
R
M
Y
R
K
S
Q
T
T
G
F
P
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XTT8
321
36288
K111
F
I
L
L
M
L
L
K
C
R
Y
P
D
R
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P22198
316
35745
A106
E
T
I
C
L
L
L
A
Y
K
V
K
Y
P
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P30366
318
36260
D108
L
F
L
G
D
Y
V
D
R
G
K
Q
S
L
E
Baker's Yeast
Sacchar. cerevisiae
P14747
604
68509
T372
G
Y
R
M
Y
K
N
T
K
T
L
G
F
P
S
Red Bread Mold
Neurospora crassa
Q05681
558
63895
T332
G
Y
R
M
Y
R
K
T
R
T
T
G
F
P
S
Conservation
Percent
Protein Identity:
100
99.4
98.4
80.5
N.A.
87.1
78.8
N.A.
81.3
N.A.
78.9
80.2
N.A.
66.8
N.A.
28.9
N.A.
Protein Similarity:
100
99.6
99.2
84.2
N.A.
93.3
90.2
N.A.
86.6
N.A.
90.3
91
N.A.
77
N.A.
41.4
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
N.A.
93.3
93.3
N.A.
93.3
N.A.
0
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
93.3
N.A.
93.3
N.A.
93.3
93.3
N.A.
93.3
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
28.5
N.A.
26.7
44.7
52.5
Protein Similarity:
N.A.
41
N.A.
40
57.4
67
P-Site Identity:
N.A.
6.6
N.A.
0
60
80
P-Site Similarity:
N.A.
20
N.A.
13.3
80
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
0
27
0
0
0
0
0
% A
% Cys:
0
0
0
7
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
0
0
7
0
0
0
0
7
0
0
% D
% Glu:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
14
% E
% Phe:
7
7
0
0
0
0
0
0
0
0
0
0
80
0
0
% F
% Gly:
80
0
0
7
0
0
0
0
0
7
0
80
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
7
0
0
0
0
0
0
0
0
0
0
0
7
% I
% Lys:
0
0
0
0
0
7
74
7
7
7
7
7
0
0
0
% K
% Leu:
7
0
14
7
7
14
14
0
0
0
7
0
0
7
0
% L
% Met:
0
0
0
80
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
7
0
87
0
% P
% Gln:
0
0
0
0
0
0
0
0
67
0
0
7
0
0
0
% Q
% Arg:
0
0
80
0
0
74
0
0
14
7
0
0
0
7
0
% R
% Ser:
0
0
0
0
0
0
0
60
0
0
0
0
7
0
80
% S
% Thr:
0
7
0
0
0
0
0
14
0
54
74
0
0
0
0
% T
% Val:
0
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
80
0
0
80
7
0
0
7
0
7
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _