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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP3CC
All Species:
11.21
Human Site:
S382
Identified Species:
17.62
UniProt:
P48454
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48454
NP_005596.2
512
58129
S382
S
D
D
E
A
E
G
S
T
T
V
R
K
E
I
Chimpanzee
Pan troglodytes
XP_001155871
512
58132
S382
S
D
D
E
A
E
G
S
T
T
V
R
K
E
I
Rhesus Macaque
Macaca mulatta
XP_001103623
511
58002
S382
S
D
D
E
A
E
G
S
T
T
V
R
K
E
I
Dog
Lupus familis
XP_851300
592
66956
H440
S
D
D
E
I
E
D
H
Y
I
S
S
Y
R
K
Cat
Felis silvestris
Mouse
Mus musculus
P48455
513
58681
T382
V
T
D
E
E
G
A
T
T
G
R
K
E
V
I
Rat
Rattus norvegicus
P63329
521
58625
G386
S
E
E
D
G
F
D
G
A
T
A
A
A
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517401
562
63623
E433
S
D
G
E
E
S
L
E
G
G
T
T
V
R
K
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080813
518
58366
G386
S
D
E
D
A
C
D
G
A
T
A
A
A
R
K
Zebra Danio
Brachydanio rerio
NP_001074063
506
57495
E383
S
E
G
D
D
T
C
E
V
R
K
E
V
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27889
570
63082
L452
T
E
E
S
E
E
P
L
S
D
D
E
A
A
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XTT8
321
36288
C203
V
P
H
E
G
P
M
C
D
L
L
W
S
D
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P22198
316
35745
L198
D
V
P
D
T
G
L
L
C
D
L
L
W
S
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P30366
318
36260
R200
L
K
S
L
D
Q
I
R
N
I
A
R
P
M
D
Baker's Yeast
Sacchar. cerevisiae
P14747
604
68509
E464
N
D
T
P
V
I
E
E
L
V
G
T
D
K
K
Red Bread Mold
Neurospora crassa
Q05681
558
63895
P424
E
D
S
A
T
T
S
P
G
S
A
S
P
A
L
Conservation
Percent
Protein Identity:
100
99.4
98.4
80.5
N.A.
87.1
78.8
N.A.
81.3
N.A.
78.9
80.2
N.A.
66.8
N.A.
28.9
N.A.
Protein Similarity:
100
99.6
99.2
84.2
N.A.
93.3
90.2
N.A.
86.6
N.A.
90.3
91
N.A.
77
N.A.
41.4
N.A.
P-Site Identity:
100
100
100
33.3
N.A.
26.6
13.3
N.A.
20
N.A.
26.6
6.6
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
33.3
N.A.
46.6
33.3
N.A.
20
N.A.
40
20
N.A.
40
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
28.5
N.A.
26.7
44.7
52.5
Protein Similarity:
N.A.
41
N.A.
40
57.4
67
P-Site Identity:
N.A.
0
N.A.
6.6
6.6
6.6
P-Site Similarity:
N.A.
13.3
N.A.
13.3
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
27
0
7
0
14
0
27
14
20
14
0
% A
% Cys:
0
0
0
0
0
7
7
7
7
0
0
0
0
0
0
% C
% Asp:
7
54
34
27
14
0
20
0
7
14
7
0
7
7
14
% D
% Glu:
7
20
20
47
20
34
7
20
0
0
0
14
7
20
0
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
14
0
14
14
20
14
14
14
7
0
0
0
0
% G
% His:
0
0
7
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
7
7
0
0
14
0
0
0
7
27
% I
% Lys:
0
7
0
0
0
0
0
0
0
0
7
7
20
7
34
% K
% Leu:
7
0
0
7
0
0
14
14
7
7
14
7
0
0
14
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
0
0
7
0
% M
% Asn:
7
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% N
% Pro:
0
7
7
7
0
7
7
7
0
0
0
0
14
0
7
% P
% Gln:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
7
0
7
7
27
0
27
7
% R
% Ser:
54
0
14
7
0
7
7
20
7
7
7
14
7
7
0
% S
% Thr:
7
7
7
0
14
14
0
7
27
34
7
14
0
0
0
% T
% Val:
14
7
0
0
7
0
0
0
7
7
20
0
14
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
7
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _