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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP3CC
All Species:
32.73
Human Site:
S456
Identified Species:
51.43
UniProt:
P48454
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48454
NP_005596.2
512
58129
S456
R
E
A
I
R
G
F
S
L
Q
H
K
I
R
S
Chimpanzee
Pan troglodytes
XP_001155871
512
58132
S456
Q
E
A
I
R
G
F
S
L
Q
H
K
I
R
S
Rhesus Macaque
Macaca mulatta
XP_001103623
511
58002
S456
R
E
A
I
R
G
F
S
I
Q
H
K
I
R
S
Dog
Lupus familis
XP_851300
592
66956
S523
R
E
A
I
R
G
F
S
L
Q
H
R
I
R
S
Cat
Felis silvestris
Mouse
Mus musculus
P48455
513
58681
T455
R
E
A
I
R
G
F
T
I
A
H
R
I
R
S
Rat
Rattus norvegicus
P63329
521
58625
S462
D
E
A
I
K
G
F
S
P
Q
H
K
I
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517401
562
63623
S509
R
E
A
I
R
G
F
S
P
Q
H
K
I
R
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080813
518
58366
S462
D
E
A
I
K
G
F
S
P
Q
H
K
I
T
S
Zebra Danio
Brachydanio rerio
NP_001074063
506
57495
P455
R
A
I
Q
G
F
N
P
Q
H
K
I
Q
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27889
570
63082
S520
K
N
A
M
Q
G
F
S
P
N
H
K
I
T
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XTT8
321
36288
P271
V
V
T
V
W
S
A
P
N
Y
C
Y
R
C
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P22198
316
35745
A266
Q
L
V
T
I
F
S
A
P
N
Y
C
G
E
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P30366
318
36260
E268
Q
V
V
E
D
G
Y
E
F
F
A
E
R
Q
L
Baker's Yeast
Sacchar. cerevisiae
P14747
604
68509
A544
S
G
V
L
P
R
G
A
L
S
N
G
V
K
G
Red Bread Mold
Neurospora crassa
Q05681
558
63895
G495
T
L
M
L
G
A
E
G
I
K
N
A
I
S
S
Conservation
Percent
Protein Identity:
100
99.4
98.4
80.5
N.A.
87.1
78.8
N.A.
81.3
N.A.
78.9
80.2
N.A.
66.8
N.A.
28.9
N.A.
Protein Similarity:
100
99.6
99.2
84.2
N.A.
93.3
90.2
N.A.
86.6
N.A.
90.3
91
N.A.
77
N.A.
41.4
N.A.
P-Site Identity:
100
93.3
93.3
93.3
N.A.
73.3
73.3
N.A.
93.3
N.A.
73.3
6.6
N.A.
53.3
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
80
N.A.
93.3
N.A.
80
6.6
N.A.
73.3
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
28.5
N.A.
26.7
44.7
52.5
Protein Similarity:
N.A.
41
N.A.
40
57.4
67
P-Site Identity:
N.A.
0
N.A.
6.6
6.6
13.3
P-Site Similarity:
N.A.
20
N.A.
33.3
40
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
60
0
0
7
7
14
0
7
7
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
7
0
7
0
% C
% Asp:
14
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
54
0
7
0
0
7
7
0
0
0
7
0
7
0
% E
% Phe:
0
0
0
0
0
14
60
0
7
7
0
0
0
0
14
% F
% Gly:
0
7
0
0
14
67
7
7
0
0
0
7
7
0
14
% G
% His:
0
0
0
0
0
0
0
0
0
7
60
0
0
0
0
% H
% Ile:
0
0
7
54
7
0
0
0
20
0
0
7
67
0
0
% I
% Lys:
7
0
0
0
14
0
0
0
0
7
7
47
0
7
0
% K
% Leu:
0
14
0
14
0
0
0
0
27
0
0
0
0
0
7
% L
% Met:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
7
0
7
14
14
0
0
0
0
% N
% Pro:
0
0
0
0
7
0
0
14
34
0
0
0
0
0
0
% P
% Gln:
20
0
0
7
7
0
0
0
7
47
0
0
7
7
0
% Q
% Arg:
40
0
0
0
40
7
0
0
0
0
0
14
14
40
0
% R
% Ser:
7
0
0
0
0
7
7
54
0
7
0
0
0
14
67
% S
% Thr:
7
0
7
7
0
0
0
7
0
0
0
0
0
20
0
% T
% Val:
7
14
20
7
0
0
0
0
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
7
7
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _