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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP3CC
All Species:
13.03
Human Site:
S498
Identified Species:
20.48
UniProt:
P48454
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48454
NP_005596.2
512
58129
S498
K
S
V
T
S
A
H
S
H
A
A
H
R
S
D
Chimpanzee
Pan troglodytes
XP_001155871
512
58132
S498
K
S
V
T
S
A
H
S
H
A
A
H
R
S
D
Rhesus Macaque
Macaca mulatta
XP_001103623
511
58002
S498
K
S
V
A
S
A
H
S
H
A
A
H
R
S
D
Dog
Lupus familis
XP_851300
592
66956
P565
K
L
V
A
A
A
Q
P
N
A
A
H
R
S
D
Cat
Felis silvestris
Mouse
Mus musculus
P48455
513
58681
P497
R
M
H
S
H
S
H
P
P
H
P
Q
A
S
R
Rat
Rattus norvegicus
P63329
521
58625
A504
N
S
I
N
K
A
L
A
S
E
T
N
G
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517401
562
63623
T549
P
V
N
L
V
T
S
T
N
S
A
D
K
N
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080813
518
58366
S504
N
S
I
N
K
A
I
S
S
E
T
N
G
T
D
Zebra Danio
Brachydanio rerio
NP_001074063
506
57495
N492
D
G
T
A
N
S
I
N
A
A
N
S
P
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27889
570
63082
Q557
T
P
S
E
D
P
N
Q
H
S
Q
Q
G
G
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XTT8
321
36288
R308
E
A
A
T
V
E
N
R
G
E
P
K
K
Q
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P22198
316
35745
S303
A
R
K
M
M
G
G
S
T
N
N
K
S
G
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P30366
318
36260
F305
D
E
S
L
M
C
S
F
Q
I
L
K
P
S
E
Baker's Yeast
Sacchar. cerevisiae
P14747
604
68509
E582
S
L
D
E
L
K
N
E
N
K
K
Y
Y
E
K
Red Bread Mold
Neurospora crassa
Q05681
558
63895
N544
R
A
T
R
E
A
D
N
D
K
K
L
Q
T
L
Conservation
Percent
Protein Identity:
100
99.4
98.4
80.5
N.A.
87.1
78.8
N.A.
81.3
N.A.
78.9
80.2
N.A.
66.8
N.A.
28.9
N.A.
Protein Similarity:
100
99.6
99.2
84.2
N.A.
93.3
90.2
N.A.
86.6
N.A.
90.3
91
N.A.
77
N.A.
41.4
N.A.
P-Site Identity:
100
100
93.3
60
N.A.
13.3
20
N.A.
6.6
N.A.
26.6
6.6
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
93.3
73.3
N.A.
33.3
46.6
N.A.
40
N.A.
46.6
26.6
N.A.
20
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
28.5
N.A.
26.7
44.7
52.5
Protein Similarity:
N.A.
41
N.A.
40
57.4
67
P-Site Identity:
N.A.
6.6
N.A.
6.6
0
6.6
P-Site Similarity:
N.A.
6.6
N.A.
13.3
20
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
14
7
20
7
47
0
7
7
34
34
0
7
0
0
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
0
7
0
7
0
7
0
7
0
0
7
0
7
40
% D
% Glu:
7
7
0
14
7
7
0
7
0
20
0
0
0
7
7
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% F
% Gly:
0
7
0
0
0
7
7
0
7
0
0
0
20
14
0
% G
% His:
0
0
7
0
7
0
27
0
27
7
0
27
0
0
0
% H
% Ile:
0
0
14
0
0
0
14
0
0
7
0
0
0
0
0
% I
% Lys:
27
0
7
0
14
7
0
0
0
14
14
20
14
0
20
% K
% Leu:
0
14
0
14
7
0
7
0
0
0
7
7
0
0
7
% L
% Met:
0
7
0
7
14
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
14
0
7
14
7
0
20
14
20
7
14
14
0
7
0
% N
% Pro:
7
7
0
0
0
7
0
14
7
0
14
0
14
0
7
% P
% Gln:
0
0
0
0
0
0
7
7
7
0
7
14
7
7
0
% Q
% Arg:
14
7
0
7
0
0
0
7
0
0
0
0
27
0
7
% R
% Ser:
7
34
14
7
20
14
14
34
14
14
0
7
7
40
7
% S
% Thr:
7
0
14
20
0
7
0
7
7
0
14
0
0
20
0
% T
% Val:
0
7
27
0
14
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
7
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _