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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP3CC
All Species:
14.85
Human Site:
T215
Identified Species:
23.33
UniProt:
P48454
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48454
NP_005596.2
512
58129
T215
I
R
K
L
D
R
F
T
E
P
P
A
F
G
P
Chimpanzee
Pan troglodytes
XP_001155871
512
58132
T215
I
R
K
L
D
R
F
T
E
P
P
A
F
G
P
Rhesus Macaque
Macaca mulatta
XP_001103623
511
58002
T215
I
R
K
L
D
R
F
T
E
P
P
A
F
G
P
Dog
Lupus familis
XP_851300
592
66956
K273
I
K
K
L
D
R
F
K
E
P
P
A
F
G
P
Cat
Felis silvestris
Mouse
Mus musculus
P48455
513
58681
S215
I
R
K
L
D
R
F
S
E
P
P
A
F
G
P
Rat
Rattus norvegicus
P63329
521
58625
K219
I
R
K
L
D
R
F
K
E
P
P
A
Y
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517401
562
63623
K266
I
R
K
L
D
R
F
K
E
P
P
A
F
G
P
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080813
518
58366
K219
I
R
K
L
D
R
F
K
E
P
P
A
Y
G
P
Zebra Danio
Brachydanio rerio
NP_001074063
506
57495
K216
I
R
K
L
D
R
F
K
E
P
P
A
F
G
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27889
570
63082
K285
I
R
R
L
D
R
F
K
E
P
P
A
F
G
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XTT8
321
36288
K36
L
I
C
E
T
Q
V
K
S
I
C
A
K
V
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P22198
316
35745
E31
N
A
Q
L
S
E
S
E
I
K
Q
L
C
A
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P30366
318
36260
T33
R
L
V
E
F
R
N
T
R
P
G
S
G
K
Q
Baker's Yeast
Sacchar. cerevisiae
P14747
604
68509
L297
I
E
E
Y
D
E
V
L
D
K
D
L
T
E
E
Red Bread Mold
Neurospora crassa
Q05681
558
63895
R257
I
R
N
I
D
R
F
R
E
P
P
T
Q
G
L
Conservation
Percent
Protein Identity:
100
99.4
98.4
80.5
N.A.
87.1
78.8
N.A.
81.3
N.A.
78.9
80.2
N.A.
66.8
N.A.
28.9
N.A.
Protein Similarity:
100
99.6
99.2
84.2
N.A.
93.3
90.2
N.A.
86.6
N.A.
90.3
91
N.A.
77
N.A.
41.4
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
93.3
86.6
N.A.
93.3
N.A.
86.6
93.3
N.A.
86.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
93.3
N.A.
93.3
N.A.
93.3
93.3
N.A.
93.3
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
28.5
N.A.
26.7
44.7
52.5
Protein Similarity:
N.A.
41
N.A.
40
57.4
67
P-Site Identity:
N.A.
6.6
N.A.
20
13.3
60
P-Site Similarity:
N.A.
13.3
N.A.
26.6
26.6
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
0
0
0
0
0
74
0
7
7
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
7
0
7
0
0
% C
% Asp:
0
0
0
0
80
0
0
0
7
0
7
0
0
0
0
% D
% Glu:
0
7
7
14
0
14
0
7
74
0
0
0
0
7
7
% E
% Phe:
0
0
0
0
7
0
74
0
0
0
0
0
54
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
7
0
7
74
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
80
7
0
7
0
0
0
0
7
7
0
0
0
0
0
% I
% Lys:
0
7
60
0
0
0
0
47
0
14
0
0
7
7
0
% K
% Leu:
7
7
0
74
0
0
0
7
0
0
0
14
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
7
0
0
0
7
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
80
74
0
0
0
67
% P
% Gln:
0
0
7
0
0
7
0
0
0
0
7
0
7
0
7
% Q
% Arg:
7
67
7
0
0
80
0
7
7
0
0
0
0
0
7
% R
% Ser:
0
0
0
0
7
0
7
7
7
0
0
7
0
0
0
% S
% Thr:
0
0
0
0
7
0
0
27
0
0
0
7
7
0
0
% T
% Val:
0
0
7
0
0
0
14
0
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
0
0
14
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _