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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GCLM
All Species:
28.18
Human Site:
S185
Identified Species:
56.36
UniProt:
P48507
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48507
NP_002052.1
274
30727
S185
W
A
Q
V
K
P
N
S
N
Q
V
N
L
A
S
Chimpanzee
Pan troglodytes
XP_513572
1102
123138
L185
W
A
Q
L
L
G
R
L
R
Q
E
N
C
L
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_855117
272
30498
S183
W
A
Q
V
K
P
N
S
N
Q
V
N
L
A
S
Cat
Felis silvestris
Mouse
Mus musculus
NP_032155
274
30516
S185
W
A
Q
V
K
P
N
S
N
Q
V
N
L
A
S
Rat
Rattus norvegicus
NP_059001
274
30529
S185
W
A
Q
V
K
P
N
S
N
Q
V
N
L
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001007954
271
30244
S182
W
A
Q
V
K
P
S
S
N
Q
V
N
L
A
S
Frog
Xenopus laevis
NP_001080413
274
30683
S184
W
S
Q
V
K
P
A
S
N
Q
V
N
L
A
S
Zebra Danio
Brachydanio rerio
NP_956139
273
30389
S183
W
A
Q
I
K
P
S
S
N
Q
V
N
L
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_732780
285
31454
L192
A
D
L
D
A
A
A
L
E
E
L
H
N
S
A
Honey Bee
Apis mellifera
XP_397174
283
31611
T190
E
N
D
V
Q
L
L
T
H
N
D
P
G
Q
I
Nematode Worm
Caenorhab. elegans
NP_491305
276
31813
I184
H
F
D
V
K
P
S
I
N
H
V
R
L
D
G
Sea Urchin
Strong. purpuratus
XP_001180090
272
30893
I183
W
A
R
V
K
P
I
I
D
Q
L
N
Q
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.8
N.A.
85
N.A.
96.3
95.9
N.A.
N.A.
77.7
72.2
63.1
N.A.
27
28.2
30
37.5
Protein Similarity:
100
24.8
N.A.
87.9
N.A.
98.1
98.1
N.A.
N.A.
87.2
84.3
76.6
N.A.
48
51.2
48.5
57.6
P-Site Identity:
100
33.3
N.A.
100
N.A.
100
100
N.A.
N.A.
93.3
86.6
86.6
N.A.
0
6.6
40
46.6
P-Site Similarity:
100
46.6
N.A.
100
N.A.
100
100
N.A.
N.A.
100
93.3
100
N.A.
33.3
26.6
46.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
67
0
0
9
9
17
0
0
0
0
0
0
59
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
9
17
9
0
0
0
0
9
0
9
0
0
17
0
% D
% Glu:
9
0
0
0
0
0
0
0
9
9
9
0
0
0
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
9
% G
% His:
9
0
0
0
0
0
0
0
9
9
0
9
0
0
0
% H
% Ile:
0
0
0
9
0
0
9
17
0
0
0
0
0
0
9
% I
% Lys:
0
0
0
0
75
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
9
9
9
9
9
17
0
0
17
0
67
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
34
0
67
9
0
75
9
0
9
% N
% Pro:
0
0
0
0
0
75
0
0
0
0
0
9
0
0
0
% P
% Gln:
0
0
67
0
9
0
0
0
0
75
0
0
9
9
0
% Q
% Arg:
0
0
9
0
0
0
9
0
9
0
0
9
0
0
0
% R
% Ser:
0
9
0
0
0
0
25
59
0
0
0
0
0
9
59
% S
% Thr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% T
% Val:
0
0
0
75
0
0
0
0
0
0
67
0
0
0
0
% V
% Trp:
75
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _