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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GCLM
All Species:
30.61
Human Site:
Y176
Identified Species:
61.21
UniProt:
P48507
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48507
NP_002052.1
274
30727
Y176
K
T
Q
L
E
Q
L
Y
Q
W
A
Q
V
K
P
Chimpanzee
Pan troglodytes
XP_513572
1102
123138
Y176
K
T
Q
L
E
Q
L
Y
Q
W
A
Q
L
L
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_855117
272
30498
Y174
K
T
Q
L
E
Q
L
Y
Q
W
A
Q
V
K
P
Cat
Felis silvestris
Mouse
Mus musculus
NP_032155
274
30516
Y176
K
T
Q
L
E
Q
L
Y
Q
W
A
Q
V
K
P
Rat
Rattus norvegicus
NP_059001
274
30529
Y176
K
T
Q
L
E
Q
L
Y
Q
W
A
Q
V
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001007954
271
30244
Y173
K
T
L
L
E
Q
L
Y
V
W
A
Q
V
K
P
Frog
Xenopus laevis
NP_001080413
274
30683
Y175
K
A
L
L
E
Q
L
Y
L
W
S
Q
V
K
P
Zebra Danio
Brachydanio rerio
NP_956139
273
30389
Y174
K
T
L
L
E
Q
L
Y
N
W
A
Q
I
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_732780
285
31454
G183
K
Q
Q
I
T
Q
L
G
I
A
D
L
D
A
A
Honey Bee
Apis mellifera
XP_397174
283
31611
T181
P
P
A
L
Q
T
F
T
K
E
N
D
V
Q
L
Nematode Worm
Caenorhab. elegans
NP_491305
276
31813
I175
A
R
Q
L
K
T
I
I
D
H
F
D
V
K
P
Sea Urchin
Strong. purpuratus
XP_001180090
272
30893
H174
K
T
M
L
E
K
L
H
Q
W
A
R
V
K
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.8
N.A.
85
N.A.
96.3
95.9
N.A.
N.A.
77.7
72.2
63.1
N.A.
27
28.2
30
37.5
Protein Similarity:
100
24.8
N.A.
87.9
N.A.
98.1
98.1
N.A.
N.A.
87.2
84.3
76.6
N.A.
48
51.2
48.5
57.6
P-Site Identity:
100
80
N.A.
100
N.A.
100
100
N.A.
N.A.
86.6
73.3
80
N.A.
26.6
13.3
33.3
73.3
P-Site Similarity:
100
86.6
N.A.
100
N.A.
100
100
N.A.
N.A.
86.6
80
86.6
N.A.
33.3
33.3
46.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
9
0
0
0
0
0
0
9
67
0
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
9
0
9
17
9
0
0
% D
% Glu:
0
0
0
0
75
0
0
0
0
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
9
9
9
0
0
0
9
0
0
% I
% Lys:
84
0
0
0
9
9
0
0
9
0
0
0
0
75
0
% K
% Leu:
0
0
25
92
0
0
84
0
9
0
0
9
9
9
9
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% N
% Pro:
9
9
0
0
0
0
0
0
0
0
0
0
0
0
75
% P
% Gln:
0
9
59
0
9
75
0
0
50
0
0
67
0
9
0
% Q
% Arg:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% S
% Thr:
0
67
0
0
9
17
0
9
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
9
0
0
0
75
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
75
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _