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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GIPR
All Species:
3.94
Human Site:
S447
Identified Species:
10.83
UniProt:
P48546
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48546
NP_000155.1
466
53157
S447
V
P
T
S
R
G
L
S
S
G
T
L
P
G
P
Chimpanzee
Pan troglodytes
XP_001164472
467
52776
G445
L
Q
F
G
R
G
G
G
S
Q
D
S
S
A
E
Rhesus Macaque
Macaca mulatta
XP_001111894
491
55343
P470
I
P
L
A
G
G
L
P
R
L
A
E
S
P
F
Dog
Lupus familis
XP_541554
466
53238
S447
V
A
A
D
G
A
R
S
L
G
T
L
P
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q0P543
460
52973
N441
C
R
E
A
A
V
G
N
A
L
P
S
G
M
L
Rat
Rattus norvegicus
P43219
455
52238
N436
P
Q
E
A
A
I
R
N
A
L
P
S
G
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001139611
430
49554
M412
N
K
E
V
K
S
E
M
K
K
K
W
Q
L
W
Frog
Xenopus laevis
O42602
415
47768
S396
A
R
V
A
R
A
M
S
I
P
T
S
P
T
R
Zebra Danio
Brachydanio rerio
Q68EK2
470
54084
L450
I
D
G
H
T
E
H
L
N
G
K
N
Y
H
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.7
48.6
86.6
N.A.
79.1
78.5
N.A.
N.A.
45.7
30
27.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
62.7
61.7
88.8
N.A.
83.6
83.2
N.A.
N.A.
61.1
45.9
47
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
20
46.6
N.A.
0
0
N.A.
N.A.
0
26.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
33.3
46.6
N.A.
20
20
N.A.
N.A.
6.6
40
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
12
45
23
23
0
0
23
0
12
0
0
12
0
% A
% Cys:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
12
0
0
0
0
0
0
12
0
0
0
12
% D
% Glu:
0
0
34
0
0
12
12
0
0
0
0
12
0
0
12
% E
% Phe:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
0
12
12
23
34
23
12
0
34
0
0
23
23
0
% G
% His:
0
0
0
12
0
0
12
0
0
0
0
0
0
12
0
% H
% Ile:
23
0
0
0
0
12
0
0
12
0
0
0
0
0
0
% I
% Lys:
0
12
0
0
12
0
0
0
12
12
23
0
0
0
0
% K
% Leu:
12
0
12
0
0
0
23
12
12
34
0
23
0
12
23
% L
% Met:
0
0
0
0
0
0
12
12
0
0
0
0
0
23
0
% M
% Asn:
12
0
0
0
0
0
0
23
12
0
0
12
0
0
0
% N
% Pro:
12
23
0
0
0
0
0
12
0
12
23
0
34
12
12
% P
% Gln:
0
23
0
0
0
0
0
0
0
12
0
0
12
0
0
% Q
% Arg:
0
23
0
0
34
0
23
0
12
0
0
0
0
0
12
% R
% Ser:
0
0
0
12
0
12
0
34
23
0
0
45
23
0
12
% S
% Thr:
0
0
12
0
12
0
0
0
0
0
34
0
0
12
0
% T
% Val:
23
0
12
12
0
12
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
12
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _