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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNJ3
All Species:
19.39
Human Site:
S447
Identified Species:
47.41
UniProt:
P48549
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48549
NP_002230.1
501
56603
S447
I
S
S
V
P
G
N
S
E
E
K
L
V
S
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113289
429
48853
S392
R
L
L
Q
Y
L
P
S
P
P
L
L
G
G
C
Dog
Lupus familis
XP_545477
501
56480
S447
I
S
S
V
P
G
N
S
E
E
K
L
V
S
K
Cat
Felis silvestris
Mouse
Mus musculus
P48542
425
48633
S388
V
P
L
S
W
S
V
S
S
K
L
N
Q
H
A
Rat
Rattus norvegicus
P63251
501
56555
S447
I
S
S
V
P
G
N
S
E
E
K
L
V
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508825
496
55630
S442
I
S
S
V
P
G
N
S
E
E
K
L
G
S
K
Chicken
Gallus gallus
Q90854
492
55398
S439
I
S
S
V
P
G
N
S
E
E
K
L
V
S
K
Frog
Xenopus laevis
NP_001156864
429
49473
I392
S
A
K
E
L
K
E
I
Q
H
G
E
Q
V
L
Zebra Danio
Brachydanio rerio
XP_001920703
523
58279
N439
M
S
S
E
I
T
Y
N
L
G
D
L
P
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52192
505
57401
C464
F
N
T
E
A
V
T
C
E
A
G
M
L
C
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
48.9
99.4
N.A.
47.9
99
N.A.
92.6
91.4
47.9
78.5
N.A.
N.A.
N.A.
36
N.A.
Protein Similarity:
100
N.A.
64.4
99.5
N.A.
63.4
99.4
N.A.
96.4
95.2
62.4
85
N.A.
N.A.
N.A.
56.4
N.A.
P-Site Identity:
100
N.A.
13.3
100
N.A.
6.6
100
N.A.
93.3
100
0
26.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
N.A.
13.3
100
N.A.
20
100
N.A.
93.3
100
13.3
40
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
0
0
0
0
10
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
30
0
0
10
0
60
50
0
10
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
50
0
0
0
10
20
0
20
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% H
% Ile:
50
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
10
0
0
0
10
50
0
0
0
60
% K
% Leu:
0
10
20
0
10
10
0
0
10
0
20
70
10
0
10
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
10
0
0
0
0
50
10
0
0
0
10
0
0
0
% N
% Pro:
0
10
0
0
50
0
10
0
10
10
0
0
10
0
10
% P
% Gln:
0
0
0
10
0
0
0
0
10
0
0
0
20
0
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
60
60
10
0
10
0
70
10
0
0
0
0
50
0
% S
% Thr:
0
0
10
0
0
10
10
0
0
0
0
0
0
0
0
% T
% Val:
10
0
0
50
0
10
10
0
0
0
0
0
40
20
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _