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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNJ3 All Species: 25.15
Human Site: T74 Identified Species: 61.48
UniProt: P48549 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48549 NP_002230.1 501 56603 T74 Y L S D L F T T L V D L K W R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001113289 429 48853 M23 R N A M N Q D M E I G V T P W
Dog Lupus familis XP_545477 501 56480 T74 Y L S D L F T T L V D L K W R
Cat Felis silvestris
Mouse Mus musculus P48542 425 48633 M19 N V L E G D S M D Q D V E S P
Rat Rattus norvegicus P63251 501 56555 T74 Y L S D L F T T L V D L K W R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508825 496 55630 T69 Y L S D L F T T L V D L K W R
Chicken Gallus gallus Q90854 492 55398 T66 Y L S D L F T T L V D L K W R
Frog Xenopus laevis NP_001156864 429 49473 Q23 Y E S P Q L I Q T I M A R D L
Zebra Danio Brachydanio rerio XP_001920703 523 58279 T66 Y L S D L F T T L V D L K W R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P52192 505 57401 T88 G I C N V Y N T N V P K K D R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 48.9 99.4 N.A. 47.9 99 N.A. 92.6 91.4 47.9 78.5 N.A. N.A. N.A. 36 N.A.
Protein Similarity: 100 N.A. 64.4 99.5 N.A. 63.4 99.4 N.A. 96.4 95.2 62.4 85 N.A. N.A. N.A. 56.4 N.A.
P-Site Identity: 100 N.A. 0 100 N.A. 6.6 100 N.A. 100 100 13.3 100 N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: 100 N.A. 20 100 N.A. 40 100 N.A. 100 100 26.6 100 N.A. N.A. N.A. 53.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 60 0 10 10 0 10 0 70 0 0 20 0 % D
% Glu: 0 10 0 10 0 0 0 0 10 0 0 0 10 0 0 % E
% Phe: 0 0 0 0 0 60 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 10 0 0 20 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 10 70 0 0 % K
% Leu: 0 60 10 0 60 10 0 0 60 0 0 60 0 0 10 % L
% Met: 0 0 0 10 0 0 0 20 0 0 10 0 0 0 0 % M
% Asn: 10 10 0 10 10 0 10 0 10 0 0 0 0 0 0 % N
% Pro: 0 0 0 10 0 0 0 0 0 0 10 0 0 10 10 % P
% Gln: 0 0 0 0 10 10 0 10 0 10 0 0 0 0 0 % Q
% Arg: 10 0 0 0 0 0 0 0 0 0 0 0 10 0 70 % R
% Ser: 0 0 70 0 0 0 10 0 0 0 0 0 0 10 0 % S
% Thr: 0 0 0 0 0 0 60 70 10 0 0 0 10 0 0 % T
% Val: 0 10 0 0 10 0 0 0 0 70 0 20 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 60 10 % W
% Tyr: 70 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _