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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMD8
All Species:
25.76
Human Site:
S224
Identified Species:
51.52
UniProt:
P48556
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48556
NP_002803.2
257
30005
S224
L
G
P
N
N
Y
Y
S
F
A
S
Q
Q
Q
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533681
351
39556
S318
L
G
L
N
N
Y
Y
S
F
A
S
Q
Q
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CX56
257
30007
S224
L
G
P
N
N
Y
Y
S
F
A
S
Q
Q
Q
K
Rat
Rattus norvegicus
NP_001094301
353
39859
S320
L
G
P
N
N
Y
Y
S
F
A
S
Q
Q
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505290
215
24409
R183
R
G
G
G
G
K
E
R
W
G
T
G
P
G
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084749
271
31208
S238
L
G
P
N
N
N
Y
S
F
S
S
Q
Q
Q
N
Zebra Danio
Brachydanio rerio
NP_001002131
267
30996
S234
Q
S
P
D
G
Y
Y
S
F
S
T
Q
H
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648904
264
30206
S232
L
E
A
S
G
D
Y
S
F
T
D
R
S
V
K
Honey Bee
Apis mellifera
XP_625217
266
30388
Y233
L
A
K
D
G
Y
F
Y
F
N
T
T
S
E
K
Nematode Worm
Caenorhab. elegans
Q23449
250
28777
F218
L
D
G
E
R
Y
V
F
E
I
E
V
A
Q
E
Sea Urchin
Strong. purpuratus
XP_783742
237
27383
F205
E
L
G
S
D
N
C
F
Q
F
Q
E
E
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32496
274
31901
S231
R
N
W
P
I
V
N
S
K
V
Y
F
N
N
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
72.9
N.A.
97.2
70.8
N.A.
59.5
N.A.
84.8
82
N.A.
49.6
60.1
37.3
56
Protein Similarity:
100
N.A.
N.A.
72.9
N.A.
98.4
72.2
N.A.
65.7
N.A.
88.9
89.1
N.A.
70.4
74.4
57.5
76.2
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
100
100
N.A.
6.6
N.A.
80
53.3
N.A.
33.3
26.6
20
6.6
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
100
100
N.A.
20
N.A.
86.6
73.3
N.A.
46.6
53.3
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
0
0
0
0
0
34
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
17
9
9
0
0
0
0
9
0
0
0
0
% D
% Glu:
9
9
0
9
0
0
9
0
9
0
9
9
9
9
9
% E
% Phe:
0
0
0
0
0
0
9
17
67
9
0
9
0
0
0
% F
% Gly:
0
50
25
9
34
0
0
0
0
9
0
9
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
0
9
0
0
9
0
0
9
0
0
0
0
9
67
% K
% Leu:
67
9
9
0
0
0
0
0
0
0
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
42
42
17
9
0
0
9
0
0
9
9
9
% N
% Pro:
0
0
42
9
0
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
9
0
0
0
0
0
0
0
9
0
9
50
42
59
9
% Q
% Arg:
17
0
0
0
9
0
0
9
0
0
0
9
0
0
0
% R
% Ser:
0
9
0
17
0
0
0
67
0
17
42
0
17
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
9
25
9
0
0
0
% T
% Val:
0
0
0
0
0
9
9
0
0
9
0
9
0
9
0
% V
% Trp:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
59
59
9
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _